nephroguyAll of this is correct except its intravascular hemolysis, not extravascular. Also look for hemosiderinuria, hemoglobinuria and schistocytes on blood smear+12020-01-21T15:57:57Z
dermgirlIs not intravascular hemolysis, it is extrinsic hemolysis, specifically macroangiopathic hemolytic anemia. FA 2020 page 423.+2020-01-25T19:02:27Z
vishnu_c_singhThis is actually BOTH intravascular hemolysis & extrinsic hemolysis.
Extrinsic = hemolysis that isn't caused by an internal defect of the RBCs, like an enzyme/membrane defect (in other words, it's hemolysis due to an external factor like a mechanical valve).
Intravascular = hemolysis that occurs within the blood vessels (RBCs get damaged as they pass through the valve). This is in contrast to extravascular hemolysis which describes hemolysis that occurs outside of the blood vessels (e.g. inside the spleen)