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NBME 20 Answers

nbme20/Block 1/Question#43 (45.2 difficulty score)
A randomized clinical trial is conducted to ...
Neither procedure is superiorπŸ”,πŸ“Ί
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 +12 
submitted by strugglebus(172),
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ehT CI luaev datiecnon 1, ihhcw nasme tath sit gnfncaisiitni

sympathetikey  Correct. Per first aid: "If the 95% CI for odds ratio or relative risk includes 1, H0 is not rejected." +2  
xxabi  Ah that makes more sense, thanks! +  
drdanielr  Since the OR or RR is a ratio, if the two interventions are equal the ratio would be 1. So, if the CI includes 1, they are "the same" or not stat sig diff +  



 -8 
submitted by xxabi(267),
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I khtin tsi hatt teh IC itecnadno teh ruebnm ""0 hiwhc mksae ti yciattltilssa fctsanniingii

kernicterusthefrog  You're thinking about CI for a **mean difference** b/w 2 variables. This question talks about **relative risk**, for which 'strugglebus' correctly asserts that *a CI including 1 fails to reject the null hypothesis*. #funwithformatting +  
xxabi  Ahhhh you're right, I definitely had them mixed up! Thanks! +1  
xxabi  #biostatsisthebaneofmyexistence +4  
conradfussurefake  So am I the only one giving no shit about CI and going straight to what they're asking about. My understanding of the question is that they're asking about the difference in cosmetic results of both the procedure which are described in the stem as the same. The study isn't about wound infection rate!! +  
fatboyslim  @conradfussurefake In the beginning of the Q stem it states "A randomized clinical trial is conducted to compare WOUND HEALING and cosmetic differences...", hence wound infection will affect wound healing. But the because the CI contained the value of 1, it is insignificant. +1