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NBME 24 Answers

nbme24/Block 1/Question#1

A researcher hypothesizes that exposure to more ...

Case-control study

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submitted by lsmarshall(201),

An experimental design or experimental study must have an intervention, by definition. Case-control studies are observational studies, not experimental. This question is technically incorrect. They wanted to amke a point that case-control studies are time and cost efficient since they don't require following patients over time or any resources besides reviewing/gathering information. Case series could not test this hypothesis.

Also, the wording "associated wit an increased risk" somewhat alludes to case-control studies only having the ability to find odds of an associations between exposure and outcome, but not establish causal relationship.

bigjimbo  classic nbme +  




 +1  upvote downvote
submitted by catch-22(19),

I woud do a retrospective cohort here. I don't think this question is correct and provides too little information to get the correct answer. "Time efficient" is the operant word here but they simply didn't consider that retrospective cohort would be a better design here as long as the variables are coded.

sherry  I agree. I was hesitating between the two choices. I still think cohort study is better regarding the "risk". I hope this kind of questions wont pop out on the real thing. +1  
soph  I think key here was they were measuring risk though +  
yex  I also chose cohort, since it is comparing a given exposure. +  




 +1  upvote downvote
submitted by soph(16),

I think key here is they are investigating the hypothesis of ammount of arsenicin water increases RISK of cancer.... best way to measure risk is case control.

nbmehelp  If they were measuring risk shouldn't it be a cohort study though? By looking at first aid.. +1  
270onstep1  They both can determine risk. Key here is the time efficiency of case-control studies when compared to cohort. +  




drdoom  welcome, O great physician of the skull and oral cavity. we revere your intricate understandings of the face, jaw, maxilla and all their tiny and hidden foramina. teach us your ways. +