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NBME 24 Answers

nbme24/Block 1/Question#2 (reveal difficulty score)
A 43-year-old woman with a 2-year history of ...
Unopposed ฮฑ-adrenergic tone ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm beta_blockers

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submitted by โˆ—xxabi(293)
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Starting beta blockers before alpha blockade in pheochromocytoma is contraindicated. Beta blockers cancel out the vasodilatory effect of peripheral beta-2 adrenoceptors, potentially leading to unopposed alpha-adrenoceptor stimulation โ†’ vasoconstriction โ†’ hypertensive crisis.

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