fuond shit nleoni: m/4op5s.har9u/ttk0/rma0im0/aa/reeccie8/tpo02:/p5ydh1.lcu4c/
epcyptrhHori uroalmnpy shretopoyaatothr (HOPA) is a esdmnryo irazceetdhacr yb het atrdi fo ssitip,itreo lditaig lubnbgci and iaunfpl rhaatohtryp fo eth lager sjon,it llieapcyes iiovngvnl hte orlwe .msilb Cbluginb si ihrrtcaedzace yb usobbul aengnetelmr of ilamtren msetgnse of het nfisger dan sote due to ooipafertirnl of usubunlag necvetnoic e.stius
m.pa.yrir. is a arre erdaertiyh coonti.ind
A raytijmo of sscae ;&t0%()9g of nordcaeys AOPH aer atciaessdo wthi pymaunlor agmencanisil ][6 or rhncioc ppuuriveats omylnprau sas.edise
olmraPnuy lsmiainnecg,a dncilnugi ymrarip [7], atttieascm gunl ecnarc nad coriihactnatr hymmap,ol cucnoat for 8%0 fo assec fo sycndearo .PHOA eonamcnociAdar fo the ulng si the most tfqrnuee nad mlsal elcl ccrinmaoa si eth lsate ntuerefq cihgsttlooiphoa yept of gnul recanc cdaseosiat thwi PHAO ][7.
otehr icdseaatos xaeoacthirrtc elicnimagans uinelcd pagloyrnhesnaa occa,nmria alnre cell aroamccni, eglaopaohse ecnr,ca gtcaris tuomru [8], naercptiac crcena, srtaeb phdoyslel rutumo 9,][ aonm,leam todiryh an,ccre mosoreosatca adn lsttnianei .yhloampm
Virosua riuacmhtleoog ioicsndnot, icunidlgn AR 0,1][ SA 1,[]1 rlepittiyaros s,onado ELS []2,1 asaakyTu eisedas 1,3[] sicrodis,aos APS nda taenniardreeM erevf are wnnok ot eb toidesacas ihwt isht doicntnio sa e.lwl
rayPuonml sondniciot uhsc as cstcyi ,firiossb ocltbruseisu, itphcaiido polmnrauy iisbrsof [4]1 dna nulg nntslpattaoarin evha aols bene cedsastaoi with PO.AH
ihTs teaintp has hehrpcptyior potyohhrtastreao hhwci is sstocaidae hiwt nbngrohcicoe arcacmino. tI rsepesnt tihw npfailu einwlgsl fo ssrwt,i rni,sgef k,leasn sneek, ro ewlo.bs In dd,iaoint het dsen fo glno nseob whos alpiestero wen nobe ifmaontro , chihw acn urdceop laidgit bclubngi nad enotf iritrahts of tanajced oitjns.
Rc:roesue lKaapn Beon hgPlyoato ageP 237
heT pittarsoenen of gBcirnconehi caomnrcai iCos-g uh and hemeTty pishs orttu aiassesttm to Lunn,binareog,B dan l.ar endas So won eth iqnsutoe is teonnnigim the aesm psitno The guhoc nad tsmpuu nda salo wen onbe mioarfton no aeecftdf oesnb on yaXr and salo nlbugibc enrpessret teh lugn.
fRc-eeenre 001 sonptcec fo onaamyt eldsi 49
Hcyopirprthe haoorosrtetaythp is a celdaim oinocitdn mboicnnig icbgnbul nda ioitrpsiste fo het mlals hnad otn,sij allyecspie the sdatil henenlgltaraiap sjnoti dan eht anematplaahcapeolgr ijtnos. asDtli pisenxnao fo hte nglo esonb sa llew as ,uiplnfa llsoewn jtiosn nda oslniyva usillov itrliopfreona rea eotfn s.een The iodoticnn amy cruoc naleo ,ipryma)(r ro ti amy be dcyoensar to asiseesd kile nlgu rcea.nc Agonm estaitnp wthi ugnl ,rceanc it is osmt aieotsscda thwi annoacrdmeicao dna estal sodsitaace iwth mlsal clel nulg can.erc sheeT saipetnt foten get ibunbclg nad nseiedcar beno noeotisidp on nglo no.bse heirT psitrnngee pmssomyt ear essiemmot loyn bgcuinbl adn nuialfp k.nslea rpcyritHophe ptoohhaasetrroty si eon of naym tatisnd ftcfee esdsdrroi ude ot rccane, hwit gunl nacecr nebgi the mtso moncmo esuca ubt soal cnuigcror with arnvioa or dnelara nilm.seagcani b) cigeorbonchn .aC dan eht noly nerswa thast earltse to ugln ecranc adn all otehr essarwn do ont. I ocshe R,A utb if yuo o'tdn k.o.nnww.o ouy w.kno
ehT eodtprer incedenic of paClna dmnseyor si 1 ni verye 0000,01 .epolep Tish has eneb a lnidnigce mernbu ued ot roewl ousexrpe to cola, ,sotbssea adn .ciials veelcrnPea of alapCn oedrsmyn is righeh in tsepinta htwi cilsia resxeupo aocmdepr to het htoer scsue.a The irtsf mcdiieeopogli sdyut ranetenkud by the sinPunimcoseoo reshceaR intU deesorvb na acdiensre rpeveeacln fo RA moansgt mne thwi sereropvsig svieams bisoifrs P().FM laMli et l.a fuond on asercndie nreceelapv fo eurhotdmai trisarhti in senirm hwen edorampc to a mtcmoinyu hwree PMF adn mdaoithuer israithrt ewre ernlpevat adn treeefroh loedndcuc htta hte iogtloye fo AR wsa tno dscoaaseti with ersexpou ot tdsu or gnlu sahcgne of epldcamocit oocmssnnepoiu.i eehrT swa a gihh plcenaevre ater of PMF and lrusbucseoti gsaomtn snriem and rxen-smie twih emrtodhaui ii4rahttr]5.[s][
pPntosaiAo:lyghyho tieaummuno iicnodnot is a mnhpeneoon ewehr oes'n obyd sah rofytammlina scell chwhi atktca sti onw uitess n,da in teh ecas of AR, teh suiy.mvon tI is vdeelibe ttha ni heset a,ptestni rteeh si na taoiantelr ihhcw eacuss teh seedrinac emimun spnrseoe to iornfeg aeatimlsr in the n.usgl rTeeh is emunim chtvyairyepti ttha si akdersp by alsici ni wihch eocsymton nda carhgeapsmo esalere eoctkiysn hcus sa tlrn-nkuiei1e dan tng-uncoaomietuegyrhpncyclamgtosioa-l-lra torcfa and muort oinsrcse farotc pa.alh ehT parsh edegs fo the ilcais asol esuca lsyis fo asollsmyo essprateo ni ageprh.smcao yhtecLmopsy are aevdictat yb het nkiceytso aeerdsle yb perg.mchaaso shTi lla dsela ot an muiumeatno neohmopenn htouhgr xrspuoee ot islica cwihh si gegeridrt in elnetycalig epsspiodder dsidvinliua owh hvea .RA
w'otdlnu het idlenynugr sasedei be AR iwchh si etnh ugiscan nhgcrebciono maciarcn?o 'Im sueo!c!ndf
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hTta iegbn da,is guln cnecdrinoamaoa yfellaispcci si setdscoaai hwit tphrrecphoyi rhota,hyttorposae hwihc is a transoeiapcapl onmsdrey ahecrtzaercid yb tgaldii igunbcb,l iarrlgah,ta tonij fnfoiss,ue and riosposetsi fo bluraut esnbo
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