Clinical use of K-sparing diuretics:

• Hyperaldosteronism
• K+ depletion
• HF
• hepatic ascites (spironolactone)
• nephrogenic DI (amiloride)
• antiandrogen

A rapid reduction of ascites is often accomplished simply with the addition of low-dose oral diuretics in the outpatient setting. First-line diuretic therapy for cirrhotic ascites is the combined use of spironolactone (Aldactone) and furosemide (Lasix) - Clevland Clinic