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NBME 20 Answers

nbme20/Block 3/Question#37

A 62-year-old man with alcohol-induced liver ...

Spironolactone

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submitted by hayayah(343),

Clinical use of K-sparing diuretics:

  • Hyperaldosteronism
  • K+ depletion
  • HF
  • hepatic ascites (spironolactone)
  • nephrogenic DI (amiloride)
  • antiandrogen
redvelvet  Patients with hepatic ascites have hyperaldosteronism; because the intravascular volume is escaped to third space(ascites). So adding spironolactone is a good choice. +  




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submitted by sweetmed(27),

A rapid reduction of ascites is often accomplished simply with the addition of low-dose oral diuretics in the outpatient setting. First-line diuretic therapy for cirrhotic ascites is the combined use of spironolactone (Aldactone) and furosemide (Lasix) - Clevland Clinic