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nbme20/Block 3/Question#28

A 23-year-old woman who is 6 months pregnant ...

Antiplatelet antibodies

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submitted by hayayah(244),

Heparin-induced thrombocytopenia (HIT) is the development of IgG antibodies against heparin bound platelet factor 4 (PF4). Antibody-heparin-PF4 complex activates platelets Ž thrombosis and thrombocytopenia. Highest risk with unfractionated heparin.