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NBME 20 Answers

nbme20/Block 3/Question#4

An 18-year-old woman comes to the physician because ...

Reactive T lymphocytes

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FA 2017: Infects B cells through CD21. Atypical lymphocytes on peripheral blood smear G —not infected B cells but reactive cytotoxic T cells. ⊕ Monospot test—heterophile antibodies detected by agglutination of sheep or horse RBCs. Use of amoxicillin in mononucleosis can cause characteristic maculopapular rash.

zup  misread the "accounts for" question as what's the reason for the atypical lymphocytes. So I answered "virus infected B lymphocytes." Anyone else misread it like that? +3  
nala_ula  Shit, I misread that too and I noticed it now. Nerves get the best of us! +  




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submitted by katsu(0),

Patient has infectious mono. Atypical lymphocytes (reactive CD8+ T-cells) are seen on blood smear for infectious mono.