NBME 20 Answers : Block 3 : #2 = A 23-year-old woman is brought to the emergency ...

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NBME 20 Answers

nbme20/Block 3/Question#2

A 23-year-old woman is brought to the emergency ...

Xanthine oxidase

+3 upvote downvote
submitted by karljeon(45),

This one was a somewhat simple question since chemotherapy --> tumor lysis --> need xanthine oxidase inhibitor (eg, febuxostat).

BUT WHY IS NBME GRAMMAR SO CRAP? PUT YOUR COMMAS IN THE RIGHT PLACE!

malou I swear I registered just to upvote your comment. #SoFrustratedToo +

+2 upvote downvote
submitted by breis(16),

Dx: Acute Monocytic Leukemia. Proliferation of monoblasts; lack MPO. CD14 + CD13+ MPO -. blasts characteristically infiltrate the gums.

A Xanthine Oxidase inhibitor is given to prevent adverse reactions of Tumor Lysis Syndrome which results from expulsion of cellular debris/material after the cell dies.

She has Leukemia- to prevent tumor lysis syndrome give her Allopurinol which is xanthine oxidase inhibitor page 435 FA 2020

+/- compasses(1),

+1 upvote downvote
submitted by hayayah(525),

Allopurinol inhibits xanthine oxidase. It is used for chronic gout as well as prevention of tumor-lysis associated urate nephropathy.

betcher I got confused because the question stem she was on an extensive chemotherapy regimen and got scared away from Xanthine Oxidase because of its potentially for interaction with 6MP/Azathioprene, but I guess since neither of those were directly stated in the question stem I should have gone with Xanthine Oxidase inhibitor to prevent tumor lysis as stated above +