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NBME 20 Answers

nbme20/Block 3/Question#2

A 23-year-old woman is brought to the emergency ...

Xanthine oxidase

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submitted by hayayah(422),

Allopurinol inhibits xanthine oxidase. It is used for chronic gout as well as prevention of tumor-lysis associated urate nephropathy.





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submitted by breis(11),

Dx: Acute Monocytic Leukemia. Proliferation of monoblasts; lack MPO. CD14 + CD13+ MPO -. blasts characteristically infiltrate the gums.

A Xanthine Oxidase inhibitor is given to prevent adverse reactions of Tumor Lysis Syndrome which results from expulsion of cellular debris/material after the cell dies.





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submitted by karljeon(24),

This one was a somewhat simple question since chemotherapy --> tumor lysis --> need xanthine oxidase inhibitor (eg, febuxostat).

BUT WHY IS NBME GRAMMAR SO CRAP? PUT YOUR COMMAS IN THE RIGHT PLACE!