welcome redditors!to snoo-finity ... and beyond!

NBME 20 Answers

nbme20/Block 2/Question#49

An 82-year-old woman is brought to the physician ...

Decreased slope of diastolic depolarization

Login to comment/vote.

 +7  upvote downvote
submitted by dbg(45),

BBs work by decreasing cAMP and Ca2+ thereby slowing SAN & AVN activity. This prolongs phase 4 of depolarization. Therefore, they are known to increase the duration of diastole (predominantly) causing both a rise in heart coronary perfusion and reduction in heart rate.

 +2  upvote downvote
submitted by hayayah(525),

Beta blockers as antiarrhythmics suppress abnormal pacemakers by decreasing the slope of phase 4 --> prolonging phase 4.

chandlerbas  piano player sliding the keys to the left ---> delays diastolic depolarization --> rate control +1