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Second Aid for the USMLE
NBME Answers & Explanations
NBME 20 Answers
A 28-year-old woman of Eastern European Jewish ...
Recombinational double-stranded DNA break repair
Defective homologous recombination is seen in breast/ovarian cancers with the BRCA1 gene mutation.
Ashkenazi Jews have a higher risk of inheriting the BRCA1 and BRCA 2 gene mutations, just another tip!
BRCA1/BRACA2 are involved in the repair of DNA double stranded breaks
Other answers: DNA Mismatch Repair: Lynch Syndrome (MLH1, MSH2) DNA Nucleotide Excision Repair: Xeroderma Pigmentosa
one does not simply “walk into morder”