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NBME 20 Answers

nbme20/Block 2/Question#37

A 28-year-old woman of Eastern European Jewish ...

Recombinational double-stranded DNA break repair

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submitted by hayayah(343),

Defective homologous recombination is seen in breast/ovarian cancers with the BRCA1 gene mutation.

johnthurtjr  Ashkenazi Jews have a higher risk of inheriting the BRCA1 and BRCA 2 gene mutations, just another tip! +  
lebron james  BRCA1/BRACA2 are involved in the repair of DNA double stranded breaks +1