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Retired NBME 20 Answers

nbme20/Block 2/Question#25 (reveal difficulty score)
A 14-year-old girl is brought to the ...
Mitochondrial tRNALeu ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: MELAS Biochem

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 +19  upvote downvote
submitted by โˆ—sympathetikey(1600)
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titosuanM ni TML1T- yhM(altcrlodinoi eecdond NRAt liueecn 1)

A nommoc tmaotiun si A32.4G3 aCn reutsl ni pltmleiu dotamilcronhi eisfcndieiec adn oteisadsca dserrods.i tI is ssoctaeaid twh:i

  • ianioocdMltrh olehhampatncopyey
  • iacLct siicdaos
  • rok-eeiktlS osedspei LSE(M)A

MEALS is a rera molochtidarin rdiersod nonwk ot aeftcf ynma rtaps of eht bd,oy silalcpeye hte onvuser tsmyes adn teh banri. sSmopmyt of LMSEA uedcil:n

  • nceuretRr vreees eheshcada
  • slceMu snweksae ot)mypah(y
  • rHeangi slos
  • Srkoitl-kee oisepdes thwi a loss of sncuscnsoes,io zei,serus dan rehto elsbopmr ngtaffeci teh osnruev semyst.

Srou:ec ./Lwt/itwiTek.e/-/rodskpihpinTaMi1:g

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j44n  i utsj was htat yeerv ssueit htat was fetdecfa adh a ihgh /aT02P uqnreremiet dan emidx thiw teh ctclia adic atht etman ehs asnwt niugs erh tlnorece snttarorp cnhia so i pdciek eht onyl earsnw htta had ritocinodhma ni it +6
topgunber  heT diaeses si SE.LMA ordhntlcMiiao cndodee tNRA enuilec 1 si hte .umtoanit pAranlptey scsiaatdoe thiw gihh teno nsedes.af tI is naarpept its lhaoidinromtc ihwt mtlaanre mntosias,snir uhtgoh noraeytutulnf het oetiolyg is utetr eiarmionotzm / sprseoc of ilmantnioei. eMayb txen eitm eht yatsrg illw cosfu omre on ladotniiormch sdesseai nad see taht isht hoceic is eht lyon cdohiilortanm erawsn cthaMioceh riicdoonl. otoanhyyhepaEcmlp tiaccL dAoiscsi koeStr elik .AEomMstSLsy"mp is a rare dlaihionrtomc doeridrs nnkwo ot cfefat yanm pstar fo the b,doy clplseeyai the svrenuo eystms dna teh ri.bna sSotpymm of SMALE ldncieu rrencuetr eseevr dc,haeseah lescmu wskneaes ,yyhm)(pato anrehgi ,osls -rkiektolse opdsiees hitw a sosl fo s,ssenccuinoos ee,ruizss and toehr mlboespr egcffanti teh snrveuo m"es5[ts].y ecorSu kiW:i +



 +12  upvote downvote
submitted by mrmassador(12)
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I hnikt the tiopn of eht outinseq si to nzecgeior ttah iths si a nohioimtdrlca sesiade mthr(oe adn anamelrt gmhdrneator were efa).tfced sdorecuP iewd rgnae fo tfece,sf tub ecsulm swsaenek dan moes gucroneilo fitisecd dotso uto to em. sloA h:tis eg.TnetgooiMghsp/iL/v.:hintl1ron-t/#cmn.nTshd/

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sympathetikey  esY, tbu ods'net thta emna lmaaretn tonrsaimsn?is enM acn ahve these sdisesae ,too etyh ustj nwot' psas mthe no. +32



 +5  upvote downvote
submitted by โˆ—hayayah(1212)
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hisT si a aiosettenrnp of mdcoloitnirah apohtmy.y hyeT fnoet nsretep tiwh tayohpy,m ctlica saisoidc, dan SNC sdsaeie. 2ยฐ ot iurflae ni dtoxaievi trnypasoploh.ioh elMucs opibys teonf hsosw edgarโ€œg erd sifbre.โ€

eTrhe si aibarevl seinrpeosx in a poaotnlupi ro evne nhitiw a iyfaml edu to tlrseohyapme in lhrtmanooiidc tnicehniar.e

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 +1  upvote downvote
submitted by thomas(3)
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t'sI a rcalmooihintd asd .-eies etrpsen in sesceiucvs eeron,sagnit sylwaa htiw aarnltme tiaor-nsnis ms dmgaea ot -inehgyregh esuisst - FCS ciltca dsiosaci ue(d ot sicraende cobrainea imlsmeaobt ued ot emradiip xiovaiedt yntaroohposhl)ip

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 +1  upvote downvote
submitted by โˆ—topgunber(67)
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eTh dieases si AS.LEM nlhraodicMiot cendeod tRNA eciulen 1 si eth ntmi.uoat atynlApper sdteaioacs hitw hghi tneo asnesf.de tI is artnpepa its altinrhdoiocm hwti aneartml nssorimn,aist toguhh yontferntauul teh itoygloe si trtue iemzoamtrino / erspsco fo nieolntiiam. ayMeb tenx imte the atrgsy wlil scofu remo on ciohonrditmla iassedse and see hatt tshi ceicho is het olyn amitrdhnlooci ernasw coihce.

  • tioiMrohdnlca oyhentpcpaEloamyh itLcca iodcAiss oekrtS ilek "ysEsSApLomM.mt si a aerr ndmiotalorchi rdseidro noknw to tfface ynam atrsp fo the o,bdy llepcyieas teh eurvnso mtessy adn het na.irb pSmmytso fo MLAES ideclun rtnrerceu everes ,ehdachsae ecmlsu eakesswn ypmyo(ah,)t inherag osls, ioelskkr-et osiesedp itwh a osls fo io,socuscnness esuiezrs, nda oerht rmlesbpo ffcnaeigt hte urosnev m5["tsy.se] re cSou :kWii
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