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NBME 20 Answers

nbme20/Block 1/Question#3

A 48-year-old man comes to the physician for a ...

Upregulation of the LDL receptors

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submitted by xxabi(137),

Statins decrease cholesterol synthesis, which indirectly Statins indirectly cause increased LDL receptor expression on hepatocytes (increases LDL clearance from circulation).

this question is gramatically wrong, just move on. i did not and wasted maybe 5 minutes. just know that when you decrease chol. , there is no chol. left, so LDL regulating people open more receptors to balance the chol. back to its normal.

md_caffeiner  and if you dont even remember what makes what, just know that when ldl is getting into the cell via ldl r., it is going directly to make some chol. +1