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NBME 20 Answers

nbme20/Block 1/Question#3 (29.5 difficulty score)
A 48-year-old man comes to the physician for ...
Upregulation of the LDL receptors🔍,📺
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 +7 
submitted by xxabi(267),
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ntstaSi ceadsree lhrecootles ni,syshset chwhi iyticrnled tniatsS treldciyni auecs rsdnceiae DLL orrepcet sipreexsno no syetecoapht ais(ecsnre LLD reaeanclc mrof t.icaoilrucn)

fatboyslim  SketchyPharm's "Statins" video explains this concept nicely and other lipid-lowering drugs +2  
skonys  Whose got your back in a bar brawl? Dr. Ryan or Andrew Berg? +  



 +2 
submitted by hellohello(9),
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I adh emos otlbeur nutgdniarsdne ywh thye ddnti kas bauto het intbihnioi fo C-oHGMa aecdetsur os did osem ermo hecsrare tnio eht DLL crretpeo aayhtwp hatt I ntasw wreaa f.o tI apspare ot be het amjor turoinobtcr to the adredesce loorechstle lev.lse eHer si a odog nisopsys fo het DLL poruungtalei wa:pytah

reLiv" lslce esens eth dcrudee veells fo revli eshooterllc adn ekse ot msetnpcoea yb zihesgnisytn DLL recoesrtp to drwa srceohoetll out of the acc.uitroinl hTsi si hoaccmlsepdi aiv eposrsate thta lcveae muondbnerbae-m ltrose artryulgoe enletme dbnigin spr,ontie hchiw tenh airmtge to hte uueslnc dan inbd to teh ltoesr erespnos semenl.et eTh slrteo sreeosnp neestmel nhte eiacialtft scerendai rcsptnirnatoi of iarvosu rohet ntr,ospie msot ayln,otb LLD ecrptor.e The LLD octrrpee si nadsoptrter ot teh erlvi llce mnambeer dna dbins to singaps LLD and LLVD actrp,lise dniiaetmg ethri kpetua otin hte elir,v wehre hte slhrloeotec si ssrerdeceop oitn ibel alsts and hreot dbp.ysucrot shiT utsesrl ni a nte eeftfc fo lsse LLD iacinctgurl in lb.oo"d




 -4 
submitted by md_caffeiner(65),
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hsti tnsuqoie si raytmiagclal w,rngo stju emvo .no i did tno dna edwsta myaeb 5 misunet. jsut nwko that nehw yuo dseaerec oh.lc , rethe si on hol.c fe,tl so LLD lnraitugge epoepl epon more rcsroeept to ancebla hte .holc bkca ot sit m.rnola

md_caffeiner  and if you dont even remember what makes what, just know that when ldl is getting into the cell via ldl r., it is going directly to make some chol. +6