Why there's no increase in Hydrostatic pressure in glomerular capillaries?
The glomerular filtration rate (GFR) depends on the interplay of hydrostatic and oncotic pressures in the glomerular capillaries and Bowman's space. The GFR increases with higher glomerular hydrostatic pressure and decreases with increasing Bowman's capsule hydrostatic pressure or higher glomerular capillary oncotic pressure. Acute ureteral obstruction increases hydrostatic pressure proximal to the constriction. This pressure rise is transmitted back to the Bowman's space, resulting in decreased GFR.
Source: UWORLD
Not a full answer but it's a start (in the context of an obstruction): "Obstruction of urine flow results in an increase in hydrostatic pressures proximal to the site of obstruction. It is this buildup of pressure that leads to the accompanying pain, the distention of the collecting system in the kidney, and elevated intratubular pressures that initiate tubular dysfunction. In the first days of obstruction, the dilatation of the poorly compliant collecting system may be minimal. As the increased hydrostatic pressure is expressed in the urinary space of the glomeruli, further filtration decreases or stops completely." (Harrison's, 20e, Chapter 313)
Asking about the CAUSE, not the response. The cause for a dilated ureter is increased GFR.
4 values are considered Pc (increases push into ureter direction) Pi (increases push into bowmans) πc (increases pull into bowmans) πi (increases pull into direction of ureter)
If ureter is dilated, the bowmans capsule is PUSHING out more fluid —> increased GFR (high Pc) and pulling less (low πc)
Got this wrong because I thought they wanted to know what the response would be...
submitted by hvancampen(7)
According to lumen, "the Bowman’s capsule space exerts hydrostatic pressure of its own that pushes against the glomerulus. Increased Bowman’s capsule hydrostatic pressure will decrease GFR, while decreased Bowman’s capsule hydrostatic pressure will increase GFR.
An example of this is a ureter obstruction to the flow of urine that gradually causes a fluid buildup within the nephrons. An obstruction will increase the Bowman’s capsule hydrostatic pressure and will consequently decrease GFR."
https://courses.lumenlearning.com/boundless-ap/chapter/physiology-of-the-kidneys/