titanesxviI think rather that high insulin is going to block the release of glucagon+12019-10-15T14:20:54Z
medpsychosisThere are three ways that Glucagon secretion is stimulated:
+(1) a stimulatory effect of low glucose directly on the alpha cell,
+(2) withdrawal of an inhibitory effect of adjacent beta cells, and
+(3) a stimulatory effect of autonomic activation.
The response of Glucagon to hypoglycemia is diminished in T1Diabetes. Hence in this pt, the impaired release of Glucagon allows for prolonged Hypoglycemia.