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NBME 20 Answers

nbme20/Block 4/Question#38

A 45-year-old man comes to the physician because of ...

Tumor necrosis factor

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Drugs like inflixamab and adalimumab are monoclonal anti-TNF-alpha antibody drugs that can be used to treat inflammatory bowel disease.

Important note - before administering, need to test for latent TB as reactivation can occur (TNF-alpha important in granuloma formation and stabilization)