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NBME 20 Answers

nbme20/Block 3/Question#31

A 62-year-old woman comes to the physician because ...

β-Tubulin

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submitted by celeste(30),

Beta-Tubulin is a subunit of tubulin. Tubulin is one of several members of a small family of globular proteins. It is the major constituent of microtubules. There are two of most common members of the tubulin family: alpha-tubulin and beta-tubulin, and together their dimers form microtubules. (origene.com)





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submitted by xxabi(87),

Vinca and plant alkaloids bind B-tubulin, which inhibits the formation or disassembly or microtubules, respectively.





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submitted by dickass(1),

Paclitaxel hyperstabilizes polymerized microtubules (made up of alpha- and beta- tubulin)