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NBME 20 Answers

nbme20/Block 2/Question#44

A 43-year-old woman, gravida 2, para 1, at 10 ...

Nuchal translucency (fetal ultrasound): increased;
Pregnancy-associated Plasma Protein (maternal serum): decreased;
Human Chorionic Gonadotropin (maternal serum): increased

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 +6  upvote downvote
submitted by hayayah(603),

Down Syndrome Labs:

  • inc. nuchal translucency
  • inc. hCG
  • inc. inhibin
  • decreased AFP
  • decreased PAPPA
celeste  I remember this as Down Syndrome has high HI (hCg and inhibit) +9  
temmy  Thanks celeste. I'll remember Hi +1  


Chart from UWorld showing different AFP levels in different conditions.

Basically AFP is elevated in everything except chromosomal aneuplodies.

+1/- hungrybox(433),

 +0  upvote downvote
submitted by hayayah(603),