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NBME 20 Answers
A 44-year-old woman comes to the physician for a ...
Could I ask why it is not Lysosomal protease
"Certain viruses have evolved to recruit the cellular E3 ligases to induce the degradation of cellular proteins that might have harmful effects on the viral life cycle. For instance, the protein E6 of Human papillomavirus (HPV) recruits the cellular E3 ubiquitin ligase E6-AP to induce ubiquitination and degradation of p53, thereby allowing viral replication."
USMLE Kaplan: A majority of cellular
proteins are degraded via the ubiquitin proteasome pathway, including many
proteins that play a role in maintaining cellular homeostasis. These include
proteins that regulate the cell cycle, apoptosis, etc.