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NBME 20 Answers

nbme20/Block 1/Question#29

During an experiment, an investigator isolates an ...


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Analysis of the elastin in the question showed a decreased number of desmosine cross-links. Desmosine is made up of four lysine residues. Therefore abnormal elastin is likely missing lysine necessary for the formation of these desmosine cross-links. Wikipedia article on Desmosine.

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Lysine is used in elastin and collagen cross linking; it is cross linked by lysyl oxidase to make collagen fibers

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