share email twitter ⋅ join discord whatsapp(2ck)
Free 120  NBME 24  NBME 23  NBME 22  NBME 21  NBME 20  NBME 19  NBME 18  NBME 17  NBME 16  NBME 15  NBME 13 
introducing : the “predict me” score predictor NEW!

NBME 20 Answers

nbme20/Block 1/Question#7 (38.1 difficulty score)
A 5-year-old girl with AIDS develops a ...
Thymidine kinaseπŸ”,πŸ“Ί

Login to comment/vote.

Tutor box

Members from the Leaderboard offering 1-on-1 help: Want to be listed here? Email us!

submitted by hayayah(1081),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

,clrAyvioc if,laromcvic ovcryvcalail are nsugnoaei .onasalg eyhT dngreuo osnrvecion ot yiolacrcv hpoapnhsmoteo iav sviru cenoedd atymeltUi,l tyeh iinithb alivr NAD yalrmepose by nacih a.ntotinimer

duMtaet liarv ynitdhime naksei anc saecu scrs.entiea

len49  Foscarnet and Cidofovir on the other hand do not require phosphorylation by viral kinase, therefore should be used in strains that are shown to be resistant. +3  

submitted by andremosq(3),

this question is asking about mechanism of resistance of Acyclovir, famciclovir, valacyclovir. They are Monophosphorylated by HSV/VZV thymidine kinase. Clinical use: HSV and VZV. Mechanism of resistance: Mutated viral thymidine kinase

submitted by nafilnaf(1),

What does she have? My assumption was that she was getting NRTIs for HIV/AIDS which get phosphorylated by HOST thymidine kinases and the mechanism for viral resistance is mutations in reverse transcriptase

azibird  I think she has chickenpox, caused by varicella-zoster virus. From FA 2020 p 183: "Vesicular rash begins on trunk; spreads to face D and extremities with lesions of different stages" +3