Supraphysiologic levels of iodine can temporarily turn off thyroid peroxidase. This is the Woldd-Chaikoff effect (FA2020 p331). Thus, high levels of potassium iodide given externally will prevent organification of the radioactive iodine and allow time for clearance from the body.
fatboyslim^ Also, potassium iodide competitively inhibits UPTAKE of radioactive iodine, and hence reduces radioactive iodine uptake by the thyroid. You should use propylthiouracil if potassium iodide is not available (Source: UW 767)+
submitted by โcassdawg(1780)
Supraphysiologic levels of iodine can temporarily turn off thyroid peroxidase. This is the Woldd-Chaikoff effect (FA2020 p331). Thus, high levels of potassium iodide given externally will prevent organification of the radioactive iodine and allow time for clearance from the body.