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Retired NBME 15 Answers

nbme15/Block 3/Question#18 (reveal difficulty score)
A 34-year-old woman who is a scientist is ...
Potassium iodide ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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Supraphysiologic levels of iodine can temporarily turn off thyroid peroxidase. This is the Woldd-Chaikoff effect (FA2020 p331). Thus, high levels of potassium iodide given externally will prevent organification of the radioactive iodine and allow time for clearance from the body.

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fatboyslim  ^ Also, potassium iodide competitively inhibits UPTAKE of radioactive iodine, and hence reduces radioactive iodine uptake by the thyroid. You should use propylthiouracil if potassium iodide is not available (Source: UW 767) +



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