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Retired NBME 15 Answers

nbme15/Block 3/Question#28 (reveal difficulty score)
A 19-year-old woman comes to the physician ...
Doxycycline ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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Tetracyclines are bacteriostatic and bind the 30S subunit to prevent attachment of aminoacyl-tRNA. Doxycycline and other tetracyclines are commonly used for refractory acne.

Other answers:

  • Ciprofloxacin is a fluoroquinilone that inhibits DNA gyrase/topoisomerase II
  • Erythromycin is a macrolide that inhibits protein synthesis by blocking translocation (macroslide) binding the 23S of the 50S ribosome subunit
  • Penicillin is a beta lactam that is a D-Ala-D-Ala analog that binds to penicillin binding proteins (transpeptidases) and blocks peptidoglycan cross-linking
  • Rifampin is an antimycobacterial drug which inhibits DNA dependent RNA polymerase
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whk123  If this can help too, mnemonic= I have to serve (30 cups of TeA) either its going to be from tetracycline or aminoglycoside family. Aminog ruled out as it is bactericidal and q.stem mentions bacteriostatic so tetra is the answer. +



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