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NBME 15 Answers

nbme15/Block 1/Question#45 (reveal difficulty score)
A 70-year-old man has a 4-month history of ...
Pancreatic enzymes ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1780)
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The description points to pancreatic insufficiency due to steatorrhea (fat in the stool, likely due to insufficiency of pancreatic lipase) and muscle fiber in the stool (which points to incomplete protein digestion, likely due to insufficiency of pancreatic proteases).

Further, he has no deficiency in carbohydrate absorption as evidenced by the D-xylose test (which indicates an intact mucosa for absorption and does not require digestive enzymes, FA2020 p373); and he has no abnormalities on biopsy of the intestine.

Thus, the primary issue is pancreatic insufficiency and supplementation of pancreatic enzymes is most helpful.

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cheesetouch  FA2018 P375 +2



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