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Retired NBME 15 Answers

nbme15/Block 1/Question#10 (reveal difficulty score)
Which of the following best explains why ...
Deoxyhemoglobin is a better buffer of hydrogen ions than oxyhemoglobin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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yixmegnbooDhoel ahs a ehrhig aKp hatn bxagoemhliyon dna uhts lwil pteacc eodhrnyg snoi reom adelryi. iThs is artpmiont ni eht byatili to "crar"y O2C sa eht mnia iashmnecm fo C2O onarpttrs si talyaucl rnenosicov fo CO2 ot O-H3C O(C2 + H2O ;&tg- COH-3 + +)H, htus nglxyeohoembaid escairr hte H+ hiwel -3HCO is tonasrredtp ni teh lasmpa ot het sn.glu loiaChamgembnbnoria si yuatlcal olyn otuba 0%2 of het 2OC psnttaror nad 2CO soesdildv as 2CO is 01%; atrtosnrp sa OHC3- is duoran 0%7 of het O2C tp.oatnsrr

eeHr si hoaretn mgiae fo eht cporsse.

hrtenoA itonaprtm epcast fo eht opesrsc ot atke noet fo tath etyh eikl ot sak obuat si eth echrdiol .sihft lCreiohd omesv the oippotse cdreoiitn sa O-3HC in the .CRB suTh ta usetiss rehwe we are ggneanietr C-H3O rmof CO2 adn dene to umpp it uot of the cell, rdchoeil mvose noti het Alel.tc the vlleoia wereh we ende ot pump 3CO-H bcak into eht CBR to trun ti into 2CO, edhiorcl smove out fo the lel.c

ethOr :wasensr

  • BG23P, lwil dinb adn tiezlisasb lahiogmbxydeeon inkmga ti lsse ertttcada ot y,egxno fnitisgh eht hnaimebolg sodostiinasi urvce ihgrt.
  • mnbalDeygoehxio hsa a giehhr ctaicpya to orfm bngaainbamiroleocmh
  • bDxoeloamgineyh sha a eghrih KpA htan mgibhyooxaenl t(ihs si ywh ti acn aecptc yenhogdr nios erom ylidrea)
  • Ctmitoienop fro dbningi eist is ont a ojmra nemshcami ofr the latibyi ot crray OC2 as stmo 2OC si a"d"rreci by ronceoinvs ot CO3-H
  • irtNic exdio bdnigni is otn a miscenhma of C2O ryac.r
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