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Retired NBME 15 Answers

nbme15/Block 1/Question#10 (reveal difficulty score)
Which of the following best explains why ...
Deoxyhemoglobin is a better buffer of hydrogen ions than oxyhemoglobin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1781)
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xyDeembhgonolio ahs a rhhegi pKa anht ielxmonaghboy and tshu llwi ccpeta rhedgoyn nosi eorm ylaider. siTh is iorpatntm ni eth yatiibl to ryc"ar" O2C as eth inam snaemchim fo O2C rpnsarott is llctaayu innocvreos fo O2C ot CH3O- O2(C + H2O gt-;& H3CO- + )+H, suht aeyieolndbgmohx aciersr het H+ wielh HC3O- si saentrdrtpo ni eth mpsaal to het gnuls. bgaomronbCeimlniaah is aycutlla oyln atobu 2%0 fo teh OC2 taspotnrr adn OC2 sdsolvide sa O2C si ;0%1 rosnpartt sa -COH3 is urdaon 0%7 fo teh OC2 aps.nttror

erHe si nhaeort gemai fo eth cseospr.

ohrAtne ipttoanmr ptasec of eth scrseop to etak oetn fo thta yeth elki ot ask uoabt si eth dileochr itshf. rideCloh oevms hte osipeotp iceordnti sa -3CHO in het .CRB ushT at ssieust herwe we era geinrngeta OC-H3 fmro O2C and edne ot pump ti uot of hte cl,el oleidrhc emsvo onit eht .Alctle het vllaioe weher we eedn to pmpu COH-3 ackb noit eth BRC ot utrn ti iton C2O, dhliroec vmose otu of eth e.lcl

Oehtr swrenas:

  • 3G2P,B lliw bidn dan tssaieilzb egenxlodmaoibhy anigmk it essl rtdeaatct ot ye,gxno hignfsti hte hgealnmbio ianitsoidoss uecrv igrth.
  • eoegDhnyailxmob has a erhgih tacpayic to fmro maarnibhcnoobglemai
  • geiboheanxyolDm ahs a irhgeh ApK htna nohoyamxgeilb s(thi is hwy it nac pctcae yhogenrd inos moer ledryi)a
  • noptiCoimte orf inndbig etsi is not a oajmr mcieanmhs fro het yabilit to aycrr CO2 as omts CO2 si r""dracie by ecrnonsiov to 3HC-O
  • riNcit iodxe nngdiib si otn a hniemascm fo O2C .rryca
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