NBME 17 Dopamine β-hydroxylase (NBME Answers)

+7 upvote downvote
submitted by ∗cassdawg(1781)

The site was recently locked🔒
It can be re-accessed by making a purchase.

Purchase your membership here

unscramble the site ⋅ become a member ⋅ $279

ensiAwnrg thsi enustoqi usreirqe nglaeer woneelgdk of eht eoalanemcthic sssyehtni pwaayth 0A(02F2 .3)8p

The coaapphr I otko ot tihs tqosneiu swa mylian nielinotaim fo rwgno srnw:sea

MAO momio(nnea eo)iasdx uolcd eb aitdimleen uecsabe seh si ialckng enhneiperip nda ciesn OMA is olvdevni in eth awnokbder of osaecclm,heatin a diiccenfye in OMA uwdlo sicerena tsnontrciaenco fo pehnieirnnrepo and htreo cea.senctamholi
nreprihepNenoi rrpsonartet cdluo eb eiamelitnd auecebs nibionhiit of eerpakut of ereipoinnrhenp u,lwod ,naaig nseierca nonrnihieeeppr etitransonconc nda she hsa seddearce t.onnrcnaticeo
Tienorsy xsyldeahyor cna eb teidinealm sbuceae it is the rtfis etps in thcociemlanae sthisyens and qrduerie fro iopndmae snyhsies,t and as hse hsa aidnrcsee naoipdem htsi pset si tno nt.ifedcie
nAmoi cdia esclaebraxd,oy ro mLoina- cdia aeybesxcalrod aosl aleldc APOD aedelycrsoa,xb si slao rerueiqd in pdneioma inhyssest dan acn be nmeidiaelt scebeua fo ehr cisreaend epndaomi tcntrone.cnioa

Tsih aevlse eht rsaen,w meoadnip ytsrbhdexaaoel.-y

unscramble the site ⋅ become a member ⋅ $279

waitingonprometric mewoAse snawer, utb sujt ot add a tbi rmoe aubot wyh teh rctreoc aneswr sakem nesse. ameonipD rae-xhydsbetaloy is teh eznmey thta rsoncetv nopdaemi to eiren.nnpieorhp rfehreeoT, teh rnecisae in poadinem oc.nc nhew rgnsii morf iuspen to t,snading si inytrg ot tell su atht erh boyd is rignamp up hte NSS to espnotamce orf lla fo hte olbod hsguinr ot reh eeft hwne esh dtssna up. Rpagnmi pu hte SNS rreiusqe ucpidronot of ece,slmanhitaoc utb wtotihu hsti ,yenmez hetssnisy of EN only gtse ot het pdnameoi gseat dan stol fo oenmpida bcask up dhebni stih .mneezy +15

Perhaps worth noting here is that Dopamine Beta-hydroxylase is a membrane-bound enzyme found in the vesicular membrane. This means that the conversion of Dopamine to Norepinephrine actually occurs within the synaptic vesicle. Norepinephrine is the only transmitter known to be synthesized within synaptic vesicles. This is mentioned in less detail in SketchyPharm 2.2 Indirect Sympathomimetics.

Also, per FA, this reaction requires Vitamin C as a cofactor!

+2/- baja_blast(219)

You must be logged in to vote!