NBME 24 Answers ↦
tinydoc
I literally got this wrong because I had the font zoomed in and assumed the 1 was on the line above like on uworld when it tries to squish the whole title in the same space x_X
+1
2019-07-16T22:12:37Z
hungrybox
Holy fuck they got me.
They boomed me. The fucking NBME boomed me.
+2
2020-02-28T17:43:10Z
graciewacie9
Amen to the PSGN question. They got me on that one. lol
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2020-03-09T01:03:43Z
msw
the psgn question is pinting to rapidly proliferating glomerulonephritis b/c the pt has developed acute renal failure within days of the insult
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2020-03-19T22:07:31Z
msw
*pointing
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2020-03-19T22:08:11Z
snoodle
HOLY GOD MY BRAIN FILLED IN THE 1. i had to read this explanation 4 times to finally see 25-hydroxyvitamin D and not 1,25. F U NBME
+1
2020-04-25T17:22:11Z
avocadotoast
this bs is prob why the question isnt on step 1 anymore
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2020-05-23T17:09:30Z
zevvyt
so since conversion of 25 --> 1-25 is disrupted , would 25 be high? I know its not an answer choice, just wondering
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2020-07-11T16:09:58Z
queezyfish
I'm confused about the phosphate level in questions like these. Decreased calcitriol would decrease phosphate absorption while PTH decrease lowers phosphate excretion. I'm assuming that the PTH decrease has the greater effect with serum phosphate levels?
+1
2019-05-29T21:32:51Z
mousie
PTH = "Phosphate trashing hormone" if PTH is high Phosphate must be low - they are always opposite (unless d/t renal failure then Phosphate will be high - kidneys will be unable to get rid of phosphate)
So low Ca d/t low PTH does not effect 25 H. Vit D ... only 1,25 H Vit D (active Calcitriol)?
+4
2019-06-03T11:11:00Z
haliburton
Clarification because I was confused: PTH stimulates kidney to produce 1,25-(OH)2 D3 (calcitriol) via 1Ξ±-hydroxylase in proximal convoluted tubule. Therefore, without parathyroid glands, low PTH, 25,D is not converted and therefore not down (normal or up). phosphate "trashed" by PTH as eloquently stated above.
+1
2019-06-11T22:25:41Z
zbird
Here the primary defect is high up from the parathyroid gland, there is decresed or no PTH which normally trashes phosphate but not in this case so serum PHOSPHATE INCREASES and the serum calcium is low because PTH should have prevented the urine calcium so there is calciuria and no resorption from bone-LOW CALCIUM, Vitamin-D is independent of PTH so stays NORMAL
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2019-07-13T01:59:40Z
submitted by tinydoc(223), 2019-07-16T22:11:21Z
ihsT setquoni si yevr ankse,y ubt ni esecsne shit is wahst nhg.peaipn
Teh tcdecnilaa arovmle fo het THP gldasn rngidu mehicdttoryyo β β THP
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ofeererhT a β PTH uwlod leda t:o
β β βPβ»Β³O β β aCβΊΒ² β β 251, yHtiyvdixonmar D
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ihsT is wogrn sa lyon ,521 tinodmvhyairyx D ouwld eb ,eadescdre eht rocnsnievos orfebe hsit aer nedo yb hte snik )uils(gnth dna lei.vr
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