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Thanks for a good answer. This question made me feel like I was taking T21 pills
Thank you- I was really thinking this question had 2 correct answers... of course my dumbass picked Mast cells.
where do i find this info??
@ajss pg 112 of first aid 2019, under type I hypersensitivity. Immediate --> mast cells releasing histamine and tryptase, late--> eosinophils and leukotrienes recruited via chemokines
Wow, i missed the fact that the question is asking for the RESULT of the reaction, NOT the cause of the reaction. Mast cells cause the initial reaction, eosinophils would be the result of the eosinophils. *facepalm
Pathophys (as far as I understand it)...Mast cell degranulates, thus the phospholipid bilayer et. Al are left behind and needs to be degraded. Who comes in? Our good friend eosinophils, as they contain Major Basic Protein (responsible from breakdown of expired mast cell).
Note, you can tie this in to the delayed Leukotriene effects of an allergic rxn, as the bilayer is also broken down by arach. Acid.
(See this link to support my credibility https://images.app.goo.gl/3cUF3ZVc7qy8uxAi9)
who else looked up what T21 pills were
I literally got this wrong because I had the font zoomed in and assumed the 1 was on the line above like on uworld when it tries to squish the whole title in the same space x_X
Holy fuck they got me.
They boomed me. The fucking NBME boomed me.
Amen to the PSGN question. They got me on that one. lol
the psgn question is pinting to rapidly proliferating glomerulonephritis b/c the pt has developed acute renal failure within days of the insult
HOLY GOD MY BRAIN FILLED IN THE 1. i had to read this explanation 4 times to finally see 25-hydroxyvitamin D and not 1,25. F U NBME
this bs is prob why the question isnt on step 1 anymore
so since conversion of 25 --> 1-25 is disrupted , would 25 be high? I know its not an answer choice, just wondering