OPMC is a ohnrroompe eepiptd ichna.
tI si tdenasrtla nad lrtae yeszmne ctu isht itedppe ni het pb.esdesptiu
cniptainsrTro si orwgn i( hda tsih to...)o cb/ tsi ont eth AmRN ttah akesm dfeeifntr eptpied sroh.enmo orroeM,ve wtha I ese nwo ,is ttha pitrrlsicantnaptsoo moidcontafii is orem or elss gic.i.nps.l so sltanrta.spto- iitonc.mfaoid enxt iemt ew ekam ti trecorc ;-)
Keswyord mfor rD. rocTu mrof lKa:npa
Even if you didn't know anything about the gene mentioned they tell you the PROTEIN serves as a precursor for making the hormones thus it has already undergone translation and the only choice that makes sense is Post-translational modification. Additionally, mRNA means it has already undergone splicing and post-transcriptional modification as it would be called hnRNA otherwise. (FA2020 pg 41)
POMC is a prohormone peptide chain that gets cleaved into gamma-MSH, ACTH, gamma-lipotropin, and beta-endorphin. There's a nice figure of this in Costanzo (Fig 9-10).
It may help to remember that pathologies with increased ACTH (ie Addison's disease) can present with hyperpigmentation since MSH (melanocyte stimulating hormone) is produced alongside ACTH.
Wyh is antaetrviel sginilcp ro scsianirrtotonpptal- oimiinafotcd n?crtoriec
It's saying a particular protein is made from this mrna, this protein is used as a precursor to produce those two hormones. so proteins once made, they need post translational trimming of N and C propeptides to be active. like trypsinogen becomes trypsin else they are just inactive protein. So any protein to work they need to go through post translational modifications.
So if a long polypeptide string is generated from signle mRNA then cleaved → post-translational modification.
If modification happens at level of RNA which is cleaved into smaller mRNA that then give proteins → alternative splicing / post-tranSCRIPTIONAL modification.