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Welcome to nerdstewiegriffin’s page.
Contributor score: 33


Comments ...

 +3  (nbme24#48)

Me: I am sorry to say but because of the consequences of your DM we will have to amputate your leg Patient: okay, but I have one question Me: yes? Patient: is fructose broken down in intestinal lumen or intestinal mucosa? Me: ..... Patient: ..... Me: I think its intestinal lumen


 +0  (nbme24#25)

Acral Lentigious is NOT associated with UV exposure. So there might be another reason

nerdstewiegriffin  Source Pathoma 2017 +
hungrybox  question doesn't have anything to do with UV exposure +1
nerdstewiegriffin  I am trying to say palms have less melanin is a wrong concept to apply. Acral Lentigious arises in dark skinned individuals and they are not related to UV exposure. I agree using melanin logic you are able to answer this Q but this logic is incorrect. and you might be aware wrong concepts don't go far. +5
greentea733  Yeah you just need to know acral lentiginous melanoma most commonly appears in African American/Asian patients. Unfortunately the question leads to to think about UV and kinda melanin, which doesn't have anything to do with what they are actually testing +

 +5  (nbme24#9)

G1 checkpoint: Cyclin D/CDK4 complex with p53 and rb G2 checkpoint: Cyclin B and CDK 1

Way to remember: G1 is associated with higher numbers D and 4 G2 is associated with B and 1

Amboss

and also F@CK me and F@CK NBME!!!

snripper  But the question doesn't mention anything about which cyclin. How does this help? +1
thyenman  @snripper I think the word choice of "mitotic cyclins" is suppose to show they wanted cyclin B which is produced in G2. This resource specifically refers to cyclin B with mitosis. CDKs and different cyclins are expressed at different stages of the cell cycle: cyclin D (G1), cyclin E (G1/S), cyclin A (S), cyclin B (mitosis). -http://medcell.med.yale.edu/lectures/cell_division.php +1

 +4  (nbme20#32)

There can be confusion between two options:

Placement of the central line via left internal jugular vein can cause damage to thoracic duct and Placement of pulmonary artery can cause damage to right lymphatic duct. However, chyle [fat + lymph] in thorax is usually caused by the damage to thoracic duct because this duct originates from abdomen so it contains fat along lymph. Thus, central line to left internal jugular vein will be more likely to cause chylothorax

Source AMBOSS

misterdoctor69  The question also mentions that there is dullness to percussion at the LEFT base of the chest and that there is substantial flui in the left pleural cavity. So we can eliminate R-sided structures such as the R subclavian vein. +3




Subcomments ...

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A onomtarlbs si an ertiumma BCR, so sti' atdeevel ni asstet fo iecdnrase .stisheoiomepa

sympathetikey  Don't mind me. Just sippin my dumb ass soda over here. +61  
someduck3  The term "Normoblast" isn't even in first aid. +36  
link981  NBME testing your knowledge of synonyms. Have to know 15 descriptive words of the same thing I guess. +19  
tinydoc  I wish they would stop making it so every other question I know the answer and I can't find it among the answer choices because they decided to use some medical thesaurus on us. +18  
qball  Metamyelocytes = Precursor to neutrophils Siderophages = hemosiderin-containing macrophage aka heart failure cells +8  
llamastep1  Theres a UWorld question about Parvovirus B19 that mentions "giant pronormoblasts" that helped me make the connection +5  
fexx  I got it right but would it hurt them to put RBCs? Medicine is hard as it is. No need to make the exams more complicated. I doubt my pt is ever going to as me if his/ her normoblasts are going to increase if they go hiking in the mountains +5  
nerdstewiegriffin  I can guarantee you this Q was written by some sadistic PhD examiner +12  


submitted by drdoom(874),
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sotnioVncatsocir gaorrin(wn fo a u)teb will ucesa het olwf trae to acnrseei rgouhth taht b,teu hhwic eacerdses irdloturdaaa/w spesr.eur heT tarfes a liudf eovsm thhrgou a ebtu, eht sles uw”tardo“ fceor ti rs.xeet (Tshi si knonw as het rtneuVi tcfeef).

hungrybox  not seeing how this is relevant +8  
sympathetikey  He's showing how A & B are incorrect @hungrybox +7  
nerdstewiegriffin  what a moron @hungrybox is !! +2  
leaf_house  MCAT flashbacks on this image +1  


Acral Lentigious is NOT associated with UV exposure. So there might be another reason

nerdstewiegriffin  Source Pathoma 2017 +  
hungrybox  question doesn't have anything to do with UV exposure +1  
nerdstewiegriffin  I am trying to say palms have less melanin is a wrong concept to apply. Acral Lentigious arises in dark skinned individuals and they are not related to UV exposure. I agree using melanin logic you are able to answer this Q but this logic is incorrect. and you might be aware wrong concepts don't go far. +5  
greentea733  Yeah you just need to know acral lentiginous melanoma most commonly appears in African American/Asian patients. Unfortunately the question leads to to think about UV and kinda melanin, which doesn't have anything to do with what they are actually testing +  


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I tge ywh tsi tlleaar tub ntdo all canarli eenvr xceept 4 isera lear?tlyVn FWT heyt dad itsh sDroo fbereo l?aaletr

qfever  I think it's the nucleus affected in lateral medullary syndrome (instead of the nerve axons) +  
nerdstewiegriffin  Because in the medulla section the nucleus is dorsal motor nucleus of X +  
doctordave  They all exit the brainstem ventrally, but the nuclei can be located deep within the brainstem +  


Acral Lentigious is NOT associated with UV exposure. So there might be another reason

nerdstewiegriffin  Source Pathoma 2017 +  
hungrybox  question doesn't have anything to do with UV exposure +1  
nerdstewiegriffin  I am trying to say palms have less melanin is a wrong concept to apply. Acral Lentigious arises in dark skinned individuals and they are not related to UV exposure. I agree using melanin logic you are able to answer this Q but this logic is incorrect. and you might be aware wrong concepts don't go far. +5  
greentea733  Yeah you just need to know acral lentiginous melanoma most commonly appears in African American/Asian patients. Unfortunately the question leads to to think about UV and kinda melanin, which doesn't have anything to do with what they are actually testing +  


submitted by nor16(58),
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MPOC is a poeroonmrh peidtpe ah.nic

It si talenstard dna atrel nsymzee utc htis iptedep in eth dbseppues.it

inTsctiropran is gownr i( hda itsh o.o..)t /cb sit tno het AmRN ttha skaem tfedefnir tpdeepi mesr.ohon o,reMorve what I see wno i,s htat atrtrnscosoapnpiilt cdfniaootiim is omre ro less ii..lpnc.gs so lstn-raatto.sp nti.doamifico etxn eimt we keam ti crrecto -);

medguru2295  This is a perfect explanation. I never knew it was the protein modified (I initially though alternate splicing too) +1  
nerdstewiegriffin  Is this an example of polycistronic mRNA? +  
paperbackwriter  @nerdstewiegriffin possibly (because it says that the original mRNA results in proteins plural, BUT the mechanism for POMC derived hormones specifically is not bc of polycystronic mRNA. Polycystronic means that you get multiple protein products from one mRNA, but in this case we get multiple PROTEIN DERIVATIVES from one PROTEIN, implying that there are some modifications/reactions taking place once we've already made ONE protein which change the protein into multiple diff. products. +1  


submitted by ergogenic22(320),
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A cethsrt jrnyui irgdnu chblrdtihi llwi treusl in ademag to eht rlatenex elrahurte adn nala ithcrpsens nad deagam ot het eladnpdu erven (.2S)-S4 iThs nca lade to aedersdec neatisons in eht eilapren dan ntaelig aare dan ealcf ro ryauirn nincteoinenc

thepacksurvives  I think that there can also be a direct tear to the anal sphincter muscles +6  
sympathetikey  A better answer choice would have been "damage to the nerves innervating the anal sphincter" but eh, ok. +20  
nerdstewiegriffin  I it is due to actual tear of external and or internal anal sphincter Source uptodate +2