share email twitter ⋅ join discord whatsapp(2ck)
free120  nbme24  nbme23  nbme22  nbme21  nbme20  nbme19  nbme18  nbme17  nbme16  nbme15  nbme13 

NBME 24 Answers

nbme24/Block 1/Question#20 (50.6 difficulty score)
Immediately after a spontaneous vaginal ...
Fusion of the sclerotomesπŸ”
tags: free 

Login to comment/vote.


 +34 
submitted by lsmarshall(396),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

Peittan hsa niapS aifbdi lcutaoc ihwhc is a nlerua ebtu cfeted irae(flu of ofsuin fo the osoerpeu.)rn mrSoclosete rae eht rapt fo ceha motesi ni a rtvtbaeree byomer nviggi srei to bnoe or ehtro aklelste sestiu. neicS a artp fo isth esiatp'nt ainsp dabfii cudldeni cssabe"ne fo oipsnus sor"scep enth a letemsorco wsa ndlvo.vie Kwginno tath rlaeun eubt tdceefs era na iesus with sinouf oslhdu be gouneh ot teg ot teh rgith r.ewnas

If the tdoorocnh ifdeal ot pveoedl neht teh neietr CNS uoldw tno oevdple sa hte rthooodcn duscine miaroonft fo enaurl l.peta

If hte lareun betu efladi to dpvleeo hnte teh oelhw CNS odwlu ont eahv .edpveodle

olkY sca si reietlarnv to shti .tnepati

nheW erluna ecsrt cell ti has etiffnrde utcsmeoo ni enfdirtfe ises.sut lerFaui of nrueal stecr ot amteigr ni ahetr nac uasec Tipssoinnraot of reatg el,vssse gToylerta fo ltlFao, or etsriePstn unsrtcu reraousits. ruiFlae of nurael srestc to tgmarie ni IG nac ecuas iphrsucsHrgn esiasde cateln(gino .eloo)angcm rceaehTr lolCsin dSynomer acn cruco ehnw nalreu srtce elcls flai ot atrigme iton t1s eagrlnyahp rc.ah ralNeu tube cesfted sha thigonn to od iwth euiralf fo unreal estcr riminaogt hugoht.

sympathetikey  Exactly. I knew it had to due with fusion of the neuropores but had never heard of sclerotomes. Thanks for the explanation. +13  
hungrybox  Fuck I picked "Formation of neural tube" but yea that makes sense... that would affect the whole CNS +3  
ruready4this  I also never heard of sclerotomes and I chose that and then switched it to formation of the neural tube because I thought that was close enough ugh close enough is not the right answer +  



 +5 
submitted by peridot(59),

Paraxial mesoderm means mesoderm surrounding the axis, aka the neural tube. They eventually form a pair of somites on either side. Somites then differentiate into:

  • sclerotomes -> vertebrae, rib cage, occipital bone (part)
  • myotomes -> skeletal muscle of the back, ribs, limbs
  • syndetomes -> cartilage, tendons
  • dermatomes -> skin of the back

Source

In this case, the patient is lacking spinous processes on top of having spina bifida. Maybe you were thinking spina bifida = neuropore defect, but what does this have to do with sclerotomes? This is what I found:

"Failure of closure of the caudal neuropore during embryogenesis will lead to spina bifida. This condition is always marked by a local lack of osteogenesis, or bone growth. The reason is that the correct differentiation and placement of underlying tissues (the spinal chord and spinal nerves and associated tissues) induce the osteogenesis, even small flaws in the underlying tissues can lead to a problem in the formation of the spine (vertebrae)." Source

So I'm guessing that when the question asks for "cause of the defect" they are talking about the vertebrae, not exactly the cause of spina bifida, which would be failure of neuropores to fuse. If that was an answer choice then def pick that, but the lack of vertebrae is due to lack of sclerotome fusion (because spina bifida could not induce it properly).




 +3 
submitted by titanesxvi(78),
unscramble the site ⋅ remove ads ⋅ become a member ($39/month)

eTshe mocltsroee cllse rfnietiadetfe otni oslharbosdnct thta mfor teh oiitracusngla rersruspoc fo the ixala enksteol nad esbon of hte ricaaln esab fro(m netetr )eriomb