need help with your account or subscription? click here to email us (or see the contact page)
join telegramNEW! discord
jump to exam page:
search for anything ⋅ score predictor (โ€œpredict me!โ€)

Retired NBME 23 Answers

nbme23/Block 4/Question#26 (reveal difficulty score)
A 28-year-old man has hypertriglyceridemia ...
Aspirin ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags:

 Login (or register) to see more


 +4  upvote downvote
submitted by โˆ—lfsuarez(160)
The site was recently locked๐Ÿ”’
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

enhW ttiepasn era ginev itcinioNc cadii)c(inaN ehyt are ldot to pxteec mncmoo esid tefsfce ot coucr csuh as wrmtah nda ednse.sr Oen cna adoiv sethe dise fteescf by agtink riaipns

unscramble the site ⋅ become a member$279$49
mcl  To dnapex no s,thi eht m/wthersnhiasrf/ldngues si ued ot esreael fo P2GD nad 2EPG ihwch is why nakgit an INSAD .spelh +20
snripper  'etnDos ecnohaitmepan hnsiibit CXO 1,2- oot? Wyh tcan' uyo eus atth tdenasi of par?iins utJs no.erngwid +4
raspberryslushy  I dha hist meas etnqoius oot, nda adh ti rdnraoew wdon to sthoe two ce.chios Eednd up ngiog anpw/isir tub it aws rots of a icno sos.t ltiSl tno rsue why 'ist tno ma.tceeopnianh +
eagleeeee  I ithkn eth nraeso si atth ciaanthemonep is ebnthiiid pierlepyralh nad is yilnam esdu ot hiiintb COX ni het CSN +8
whatup  ehT trwos edis tceffe of cinNai si .itothyicetaopx inteconpAaehm si fmyloasu nwnko ofr tipiaetcxhoy os psairni is a terbet wsenra +4
doctordave  pnemioehnAtoc is na ptntiirceya and necaliga,s tub ti is not n,fnttirmliyaamao os it outldw'n be lfuesu fro iacnNi dcideun fiulshg.n S(ee hystekc pahrm ofr A)SNsDI +3
meja2  tpeAncihmnioe lamnyi sntihiib ,-2COX utsh uwodl edla to ibhnoniiti fo nutcipdoro of tneruekieoLs, nda oerm sonldprtgansia wlli be eadm mfor iichoarnadc caid olyn etntgig up by [X1O- C I brmeemre isht by unsgi ist e,mna w-mootinn-Ahecep for OX]2-C +
fatboyslim  aebMy anisipr is oncesh evor taceenamnpiho aeesbcu iiprsan irryviebesrl nitisibh COX +

COX-3, a splice variant of COX-1, has been suggested to be the site of action of paracetamol, but genomic and kinetic analysis indicates that this selective interaction is unlikely to be clinically relevant. There is considerable evidence that the analgesic effect of paracetamol is central and is due to activation of descending serotonergic pathways, but its primary site of action may still be inhibition of PG synthesis. The action of paracetamol at a molecular level is unclear but could be related to the production of reactive metabolites by the peroxidase function of COX-2, which could deplete glutathione, a cofactor of enzymes such as PGE synthase.

https://journals.lww.com/americantherapeutics/Abstract/2005/01000/Mechanism_of_Action_of_Paracetamol.8.aspx

But mainly, Acetominophen is an antipyretic and analgesic, but it is not antiinflammatory, so it wouldn't be useful for Niacin induced flushing.



 +1  upvote downvote
submitted by kungfupanda(5)
The site was recently locked๐Ÿ”’
It can be re-accessed by making a purchase.

Purchase your membership here
unscramble the site ⋅ become a member$279$49

eaptonncheimA ctas yb niibgiitnh the O-X3C in eth NCS dna nheec eerdcgnais eth body attemurere,p but ton no the hplraeeipr X-OC1 m&p;a 2. ene,ch isnpirA si teh rbttee eccoih

unscramble the site ⋅ become a member$279$49



Must-See Comments from nbme23

ferrero on Precapillary resistance
yotsubato on 99%
sne on Triglyceride
sajaqua1 on Area labeled โ€˜Dโ€™ (Spinothalamic tract, right)
stinkysulfaeggs on Hypoglycemia
hayayah on Iris
soph on Peak inspiratory pressure (alveolar): ...
seagull on Area labeled โ€˜Cโ€™ (Cranial nerve 8: ...
water on Dietary change
wired-in on 28.8
beeip on Binding of permeable ligand to nuclear ...
thomasalterman on Hypoglycemia
yotsubato on Inhibition of the cytochrome P450-dependent ...
seagull on Decreased sodium bicarbonate reabsorption in ...

search for anything NEW!