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NBME 21 Answers

nbme21/Block 3/Question#4

A clinical trial is conducted to compare the ...

Surgical procedure group: 400; Medical management group: 400

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 +12  upvote downvote
submitted by beeip(65),

I might be the only person on earth who got this one wrong, but regardless:

"ITT analysis includes every subject who is randomized according to randomized treatment assignment. It ignores noncompliance, protocol deviations, withdrawal, and anything that happens after randomization."[1]

yo  You're not. I also goofed. +3  
seagull  https://www.youtube.com/watch?v=Kps3VzbykFQ This video is a pretty decent explination worth your time on the subject. +2  
hungrybox  I got it right but I was only like 50% sure. So I appreciate it. +  




 +7  upvote downvote
submitted by sympathetikey(358),

• Per Protocol - Only include patients in the results who followed the protocol

• As treated - Data wise, only treat the subjects as they were treated (ex - if experimental patient does what the control patients are supposed to do, move that experimental patient to the control group

• Intention to treat - Include all patients in the groups they were originally randomized to





 +0  upvote downvote
submitted by sympathetikey(358),
• Per Protocol - Only include patients in the results who followed the protocol • As treated - Data wise, only treat the subjects as they were treated (ex - if experimental patient does what the control patients are supposed to do, move that experimental patient to the control group

Intention to treat - Include all patients in the groups they were originally randomized to





one does not simply “walk into morder”