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NBME 21 Answers

nbme21/Block 2/Question#23 (27.9 difficulty score)
A 4-year-old boy with chronic granulomatous ...
Macrophages producing interleukin-1 (IL-1)🔍

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submitted by usmle11a(63),
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NFI y wlil tiihnib iftaneidfrentoi of hT2 lelcs dan ertrheofe e,a( bgwnr)o) ygtrulaero T clesl)d if the esca wsa glktnia aubot risvu

teepot123  fa 19 pg 108 +  

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submitted by temmy(112),
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IFN mgama mutlistaes cehaoarpmgs ot oedcrpu sulonaargm

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submitted by meryen13(9),

interferon gamma will do a few things in body--> 1 activate macrophages to kill! or to become epitheliod histiocyte to wall off infections. 2- it will increase the mac molecules on the surface of the cells. 3. it inhibits differentiation of t cell to th2 cell because th2 has anti inflammatory (il-10 secretion) and eosinophilic activation function. 4. also activated the nk cells to start killing!

bbr  and (just for completeness), promotes Th1 +  
ege  what does "Mac" stand for? "it will increase the mac molecules of the surface of the cells." Thanks! +  
saqeer  mac= membrane attack complex +1