Yo dawg we all about PVT TIM HaLL
Phenylalanine, Valine, TryptoDANK, Threonine, Isoleucine, Methionine, Histidine, Leucine Lysine
1. "Three HAL fans will try meth"
a. Threonine = Three
b. Histidine; Arginine; Lysine = HAL
c. Phenylalanine = fans
d. Valine; Isoleucine; Leucine = will
e. Tryptophan = try
f. Methionine = meth
essential Amino acids (AA)
1) Adults require 9 (AA) = able to make argnine via urea cycle 2) Children require 10 (AA) = they are still developing 3) With PKU tyrosine becomes essential in both adults and children
Let's say you didn't know methionine was essential.
(A) Alanine -- you can create alanine from the enzyme ALT (alanine aminotransferase), thus this enzyme cannot be essential
(B) Aspartate -- you can create aspartate from the enzyme AST (aspartate aminotransferase), thus this enzyme cannot be essential
(C) Glycine -- this one is low yield, but it is made from serine (serine + THF -> CO2 + Me-THF + glycine). If you didn't know about this, you had a 50/50 shot
(E) Tyrosine -- you can create tyrosine from phenylalanine (unless of course you have phenylketonuria), and thus this cannot be essential.
For anyone confused trying to follow @usmleuser007's comment
Slightly modified
Essential amino acids mnemonic "Ah, Three fans will try meth"the
Ah = arginine, histidine
Three = Threonine
Fans (phans)= Phenylalanine
Vill (will -- German accent pronouncing English word "will") = valine, isoleucine, leucine, lysine
Try = tryptophan
Meth = Methionine
The way I remember the essential amino acids is by referencing the amino acids groups I already know. So the essential amino acids are:
The branched chain amino acids: Isoleucine, Leucine, and Valine
The ringed amino acids EXCEPT Tyrosine (which becomes essential in those with PKU): Tryptophan, Histidine, Phenylalanine
The sulfur containing amino acids: Cysteine and Histidine (You will see debate over whether Cysteine qualifies as essential or not)
The two you just have to memorize: Threonine and Lysine
a little misleading her increase in weight made it seem as if she had low thyroid hormone and tyrosine is a precursor.
B12 comes from protein and is a necessary cofactor for methionine synthase. Low B12 = low methionine.
Methionine is an essential amino acid. All others listed are not.
submitted by โusmleuser007(464)
If you couldn't remember which were essential; then alternative would have been to realize that growing children need cells to divide. This requires DNA replication and translation. Of which the nucleic acid thyime is important. It requires a methyl transfer.
This is where methionine comes in. Methionine combines with ATP to form SAM (a methyl donor)