kardMucus hypersecretion --> Induce airflow limitation in COPD
"potential risk factor for accelerated decline in lung function"
Cigarette smoke impairs both the phagocytic and respiratory burst function of neutrophils!
Macrophages-->activated by cigarette smoke extract to release inflammatory mediators
COPD--> alveolar macrophages and neutrophils are defective in their antimicrobial functions.
Macrophages from COPD patients--> show reduced phagocytic uptake of bacteria.
"Streptococcus pneumoniae and nontypeable Haemophilus influenzae"
I Hope This Helps...+2019-08-28T05:41:13Z