Niacin( Vit B3)
- inhibits lipolysis ( hormone sensitive lipase ) and hepatic VLDL synthesis /secretion .
Side effects :
Facial flushing , secondary to prostaglandin release . Pre treat with NSAIDS
- Also causes Hypergl;ycemia and Hyperuircemia , as such avoid in Gouty patients and Diabetics
Fish oil, from FA 2019: "Believed to decrease FFA delivery to liver and decrease activity of TG synthesizing enzymes" God this Sketchy was awful
Increases catabolism of LDL cholesterol - statins (I think? I found this article https://www.medscape.com/viewarticle/412688_2) Inhibits cholesterol uptake - ezetimibe Activates PPAR alpha - fibrates Inhibits HMG CoA - statins