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NBME 16 Answers

nbme16/Block 1/Question#16 (9.7 difficulty score)
A 40-year-old woman is brought to the ...
Decreased function of Na+–K+ ATPaseπŸ”

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submitted by bingcentipede(219),

Dudes and dudettes, let me tell you how high yield Pathoma Ch. 1-3 are. Dr. Sattar is the freaking man.

Anyway, this is reversible cell injury because of swelling. If the Na/K ATPase is not working, Na is not leaving. Na follows water, so water is getting stuck in the cell, leading to swelling.

Most important is recognizing that it's reversible cell injury - everything else (except PFK lol) is talking about cell death

cassdawg  Love this explanation lol Dr. Sattar for president. FA2020 p207 for anyone who wants more details. +3  
the_enigma28  Ribosomal disaggregation (detachment) does occur in reversible cellular injury, but that is not the mechanism of cellular swelling! +1  
topgunber  this last comment is extremely important to recognize when asking about reversible injury +