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NBME 15 Answers

nbme15/Block 4/Question#40 (8.2 difficulty score)
An 18-month-old boy with severe combined ...
Irradiated packed red blood cellsπŸ”

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submitted by cassdawg(959),

From what I can tell, the gist of this question is that he has SCID and since the SCID child has basically no immune system (particularly because the lack of T-cell immunity) there is a higher chance of transfusion-associated graft versus host disease (TA-GVHD) so blood products have to be irradiated.

Here is a medscape reference with who requires irradiated RBCs due to increased risk of TA-GVHD for your perusing.

i_hate_it_here  Just curious, are you a student? Your answers are always much appreciated. +2