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Welcome to bartolomoose’s page.
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Comments ...

 +2  (nbme21#44)
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The meaudnn rdgu lcsas ni uoneqtsi are teh roolcagcy,mtse teh two tsom tneabol nebig oylcrnom nda nrclomdoei


 +0  (nbme21#7)
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ihsT neo is rilafy ioglcla if yuo eremmebr ttha eatraibc ELOV our ron.i oS umhc s,o ttha oru oybd ceam pu tihw a ywa raondu t.i eWnh an neonctiif is etdedect yb eht bdo,y it skmea kiel a osyadmdo prppere adn obsnat ndow eth ht.asche

"llA teh iorn oint teh bsoen, iqcuk i)rf(t^er!ni eidH ti orfm het !dierusrnt Gte soteh iron yreviedl strukc rf)ei(irtn ffo hte aord !o)do(bl

hiwt casedered ririfnet scome a redescae captyaic ofr ninbgid roni in the lbood

cooldudeboy1  i like the way to remember acd but there is no bacterial etiology in Rheumatoid arthritis is there? +
the_enigma28  The body recognises chronic inflammatory states as infections +
fatboyslim  Ferritin is not the "iron delivery trucks", that's actually TRANSFERRIN (transfers iron to liver and bone marrow). Ferritin is the STORAGE form of iron in the liver and bone marrow. In anemia of chronic disease, there usually is an inflammatory process going (whether infectious, auto-immune [as in this case of Rheumatoid Arthritis], or cancer). During inflammation, the body releases IL-6, which releases hepcidin. Hepcidin downregulates ferroportin channels in the gut and on macrophages; therefore you absorb less iron from the GI and iron is trapped in macrophages (ferritin) and cannot be used for RBC production. All this causes INCREASED FERRITIN, decreased TIBC (if ferritin goes up, TIBC goes down and vice versa), and decreased serum iron levels and TIBC saturation (the bone marrow will suck up all the serum iron to make RBCs because it cannot make use of the iron stored as ferritin). +8




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submitted by nwinkelmann(285),
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So I keldoo noti ihts htferru oto cuabsee I eytrpt umch konw onigtnh auobt the mkae pu of ensme. mrFo hte crreseha I fu,ond as as dsetat below by ,yo recuotfs si eht tmso tpomiratn uosttcinetn fo semne ni setrm or mepsr cnnfiout. eolwB si onantorimfi I dfnuo ot essradd eth terho eanrsw cc.esiho

niZc indccefyei i(n mrseu,) rep F,A sha nebe dtaemilcip ni addeeyl nowdu agnie,hl peerusspsd miu,ntyim elma oipyhnmado,gs edrceased dluat rhai ,(xlarayil ialacf, iu,)bpc egsysiad,u smain,ao aitcmmirrseatod tpnetraoiahce e(fdcet ni tnnalietsi nczi ),tsrbopiaon nad yma orspepdsie to choiloacl rsriicho.s AF d'dtin eycsfip eht esllve ni eht nmes,e tbu rep het leobw lri,eact lnesmai zicn enttcon swa fnuod ot hvae rno rtolncoreai to nmeesmsepr/ vvyitteacllcite.e// I t'nod ownk if erwe' udpoepss ot ownk ,ttha utb won I ,od l.lo u/btwho.tpseh7.3:7nwbm3//np/5wvin5d0.icl.mg.

As yuongbhrx m,nteodien usneilmel si lnyo teiondnme coen ni FA sa a atreetntm fro naiet, so I kloode itno it ruhrf.et Seimenul is a ntnecto of eenms, tbu leelvs rvay so hmcu that ti eevssr on spnotgirco nlclaic ecnrleeva ot rifn,iteiytl erp tshi :eiclrta u/pselmni.ci0/.nw13.p:3w.m5bt/b/whon2vgt2dh.

To elru tuo all of eth sesnwra secbua(e I id'ndt llryea nkow aghntiny uatbo het yautiql of mnes,)e I dnouf hist "yB tassitttsc-,i reeth aws on iicfantisng drfieecenf ni eth emnse aN tnconctoinrea gmnao het fidrfneet gsoupr 7( ruspog attlo sbaed on sepmr u,cnto) iangcdinti eth igaifininstnc lreo of Na in emrps iiyt.motl." 1.2/v2..enwmg/ct1ulnp:ondhb/5tsiwpihwm/7b..

ylnFlia, I 'odnt hiknt teh ah-5lpa ereutsdca eemyzn is allucayt in n,esem ubt I lucdo be g.rwon Erehti ,yaw ti td'wlonu be mnbalolrya tlevaede ro olw fi het eosttteonsre sevell rae mnl.ora

bartolomoose  as per goljan, selenium is involved in glutathione peroxidase +  
chandlerbas  selenium has a role in glutathione peroxidase. excess selenium = garlic breath, hair loss, and nail changes, might see peripheral neuropathy. deficiency (pt on TPN) = dilated cardiomyopathy +  
chandlerbas  also zinc aids in sperm motility https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773819/ thats why i chose zinc but whateverrr im over it +  


submitted by usmleuser007(377),
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Cencifdoen nlteviar ceinaesrs hwit dderecaes samepl .iesz

usmleuser007  would require a a large sample size to see if there is a true difference +  
claptain  This question is bogus. CI does not always increase with decreased sample size or vice versa. Four readings with small variation would give a narrower CI than 10 readings with greater variation. The only thing you can be certain about by adding more samples is that the CI will most likely change, but which direction is uncertain. +8  
bartolomoose  Recall the formula for 95%ci Mean +/- 1.96* (SD/sqrt(samplesize)) +1  
the_enigma28  @claptain The point you made is relevant in studies involving random data. But in case of this question, the data being collected is in fact the diastolic BP. We take several readings of BP to rule out white-coat hypertension and have as accurate reading as possible. In this case, taking more readings will actually narrow down the confidence interval. The readings here represent physiological parameter, which wouldn't vary veryyyy widely in an individual. +  
lowyield  @claptain i was thinking the same thing but ended up choosing the increased because alot of NBME seems to reward the more simplistic answer than the overthinking answer +