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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(630)
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I tknhi het oesrna oyu edne ot ctinej pdniorogtoasn in tihs aces si eeaucbs you ndee FSH adn LH to ucdpero sprm.e SFH misatlsteu the rlsieto lscle, hhiwc eiln eth ienofmissuer tsuuleb and elhp hte speoaatinogrm crdupeo metyorptcsa.se rostToneeste is a rtoupcd of geyLid sclle when eeyhrt' emustaitld by ,LH so jgitnneic sototseernte louwd aspysb thta spte ubt it lwnduot' lrayel lphe htiw .opeeesitsrmsgan eH,rewvo nncejiitg nGHR osal to'sdne no'etsd raeyll hepl ubaesce oyu dnee thta ptuislela RHGn ta ghtin to amek HL nda FHS awsreeh lnn-icagogt GHnR nlaagso aclauytl cedarees LH dna FSH nuotpc.rido

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m-ice  idngAd on to eth rnseaw aoveb. I was suktc etewenb hte orotgdpinaon iincotjsen adn pmih.eenclo Btu, clioemehpn csat to casreeni tycatiiv of nGRH whhic ethn rxstee ist fetecsf no eht piatri.ytu eTh amn in hsti tueiqnos hda his titayrpui oemdrev ceasbue fo na aamo.ned ,oS eh seend the FSH adn HL clid.trye +28
mousie  !gaeer a lRom ve of hte ptaiutyri uwldo case a fcdtiei in onsrpGtodnoai L,(H F)HS dna rretehfeo notghni to uisamelt eth tstsee to amek er...msp gaenciplr eht T thwi a chpta wodul ont auittslme the stetse to aemk remps dna if ihs saxi asw nictat htuolh(ag sti no)t htis duwlo rhfeutr nodw teaelgru the onotudripc fo mre.sp I tedamlniei inlehoempC seaubce fi eh sdonet ahev T to inedcu nategive clnufeine on eth latmyashphuo he lwli veha edaerscni GRHn and fruhter ranicgnies it iwth iepmCnolhe udwlo otn rccreot teh cetifid ni nidapGoosnot.r +5
neonem  Oh ..duh. htta maesk mhuc more ne.ess hsakT!n ..sP I thuoght hcepimleon was mero of a ltfieyitr ugrd ofr ne,wom nicse ti cbolsk vaeginte ebecfkad of gtseroen no hte yoaialy/pahrtuthptiums. uBt in men the mytess si nduer dbcefaek due to oetroetts,nes tno .ntrseego +6
utap2001  meolhice np si goreenst uegoan,al toceiivtmpe anga,itnots not fcieevtfe in n.ma 2. ehT nimaecmhs fo ienoelhmcp is faeckbde rieacens fo ;G-Htgn&R secierna F,SHLH, nto vfceeetfi ni tayupitri vlmreoa .ttanipe +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)

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 +3  upvote downvote
submitted by โˆ—asharm10(37)
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os ihs uaytrpit odaname was em,evord so rollyp shtooprgaond ewer eovrdem hwti i,t os fi uoy vegi rhng it w'not do gahitnny sa it tc;na eucdpor /HHLSF so uyo geiv hfl/hs riedtlyc to nedci ossgasinmreepet adn otste sytsesnhi.

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faus305  eahY shit smake a lot of .ncesi eTh nirerato itrtpayui upsdorce PF-GLiTA FS(H, LH, CHAT, S,TH tl,niPcoar and oGwtrh ).eooHmnr yuiitatPr sdonamae rea tosm moclmoyn alncitpaorosm ni teh rtneoiar auitp.tryi eH is sutj now ingcotin hte sfecfte of tno aivhgn LH dna F,SH tleyitini.fr So we edne ot ereapcl st,oeh aak vgie in.aogdnsotrpo +


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