NBME Free 120 Myeloperoxidase (NBME Answers)

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Retired NBME Free 120 Answers

free120/Block 2/Question#17 (reveal difficulty score)
A 6-year-old girl is admitted to the hospital ...
Myeloperoxidase 🔍 / 📺 / 🌳 / 📖
tags: biochem repeat

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submitted by ∗itsalwayslupus(48)

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Fmro oamahtP hC. 2 p.g :14 PMO ficedicyne sserult ni dfevcteie vsooecnirn fo 2OH2 to OCH.l arceIends skri for adidnaC ixsfnn glh(htuoa msto isnaeptt .otayimm)pacts uebioNtrl riauloztmet ttes is alnomr eesuacb hte rtsreropayi urtsb is allcauty lltsi t.acint sThi npeiatt sha dincdaa cnnteoifi adn ,yealded but tsill can llki ashtp ,a wihch iselgnmye gose gnalo tiwh eth aftc htat het roryipeasrt srtbu is illst ttcn,ai tbu thiotuw POM ti aym be riednedh a t.tllei

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namesthegame22 Nei!c ,eYs eth BNT tste is nrolma wiht .PMOD If it ays,s "A ltnuiobre zuarmilteto stet wshos eeitfdcni dtiunocer by rly"ncosugeat = GDC! +

Myeloperoxidase deficiency (MPOD) is a common inherited immunodeficiency syndrome characterized by the inability to produce hypochlorous acid within phagolysosomes. The disease is typically mild and may present with recurrent Candida albicans infections.
CGD is caused by NADPH oxidase deficiency and results in impaired intracellular killing of pathogens. This presents as recurrent pyogenic infections with catalase+ organisms such as S. aureus with normal concentrations of leukocytes and immunoglobulins.

+/- namesthegame22(14)

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submitted by ∗amy(4)

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So htat si to sya BOHT APNCHGD(D ixedsoa fidiccyn)ee DNA oereyalMdsipeo dyieecncif ropesdiessp ot cv-itpiaeasastole bgu ftnen.oici

220F0A P190 yoln smepaidezh no D"GC pttaien rea at dnesricae ksir rof eoftcinni yb eac+stala eiepcss bcpalea of aulzetginrni hirte onw ,22HO ilganev atgheycops uhiottw ORS for gnhgiift et"nfi.inco uBt entyapr,pal orgdiancc ot hsit eqtiou,ns tihs enmtttase hdols utre ot oyprsMleedoeia ifeccyiedn as elwl

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submitted by ∗ilikedmyfirstusername(19)

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Wyh not eiudseropx tm?eaduiss Ist eht tpes rhtig in teebwen NPDHA oci(hrnc mlntuagosrauo i)asdsee adn OPM

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ilikedmyfirstusername I egsus atth odluc tynitploeal fsieanmt as na vnee roesw pephotyne in D?SIC +1

thekneesofbees Its abeeucs ODS mfsro O22H, utb 2OH2 si eknrbo dwno yb .altcasea Sicen Spaht uAurse si asetaacl tiipvoe,s ti wo'ltnud be edikll yb it anyay.w +7

minion7 okeesnset@behfe ,,,,, so if tanepti has SOD CIINEDEFYC, eh ntac eegrenat H,02,2 so he si mhuc mero tspilubecse to teg ekldli by ia?rons?mg +1

topgunber hTe stirf tgihn to eekp grtt:iahs reacnoits ni BsCW era eatnm to ascrenei .ROS.. lhewi ertinscao ni rheot clsel aer ot egt rdi fo S..R.O eioxeudpsr si humc sngroret thna h2o2 d(an si wtha rew'e tnetgsi wthi the irrapeortsy srtub etts fro CPH-GANDD esOdaix ).diceyefinc dSei :noet SOD denifceicy wludo afestnim sa uol sehgirg' aeediss A)(LS besauec exuspordie si os xoitc it adsaegm het lecsl elrete.mshstfAev SDO roskw on O, ti keasm .2OH2 riasxdpooleeMey tkeas H22O nda tsrun ti iont helcab -Hl)O(C. hTe uqseotin si ynplmgii hatt OHBT iaaddcn nda pshat tcnano be lkeidl by sith tpaet.ni eTyh rae htbo aescatal to-piives hits mesna htat fi het nttapie c'tan urnt O22H itno teh sgrnetor OlC-H hten eht alacstea eviospit sasngmior nca utsj nrut oh22 onti wraet and go.xyen peho htat asekm ssnee. +3

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submitted by mdmofongo(0)

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ieeMoolseaxyrpd is teh loyn eon tclluyaa nleovivd ni amknig eref arcl.iasd aeCsltaa emask H2O2 tino rea,tw prueoxSeid adesmsuti mlasieenti yogxne ai,dasrcl HDL meksa altceta o(n eolr ni aelicrtab li,in)lgk nad ON ,asynesth kmaes .ON

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b1ackcoffee I ogtthhu SDO soal osemc )ne(scdo ratfe atpawyh agmkn(i h22)o to mkea lCHO— +1

mdmofongo owN htta I took a loko ta the wathypa aanig uoy rae r.hitg gKowinn ihst ’Id sya taht rfee lidsraca of 2O tisll ehva a cnhcae to uesac oems ad,eagm sa ewreh orHynegd droxeiep jstu ssvere as a itnretadeeim fro free rcliada mriatonof. husT OSD ccnfiiedye alsvee esmo ctiadlcrebai ctoian but OPM vaesle e?nno +2

igurl11 oS I smesdi hsti oto cb I was nkligoo for NPADH Ox b(c I pidnretteer ddaeyle itcoan astgani Stpha A as ON eefctf no atlaesac .+) eTnh yirbfle dcroedsien MOP htne kdcipe DSO and veodm on. tBu OMP kmaes nssee bc sti edndee to ekma lehcaB w(oh lupethinros i)kll tg&;- fDe gt;&= aCdanid .cnioeitfn hWat they amen yb dayle ni yiiavtct rfo atphS is tganilk obatu het xtare tpse nedede to esu eth aesatibc'r onw 2O2H to hnet ekma le.h..Bac utB jstu as the icbartea is gkainm 22,HO t'si loas reognmiv ti nuisg ala.seact So it tkae a ieltlt gelorn ot evha uhegno lhbaec to haev a ailitcrcbade fc.etfe +

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submitted by ∗stunna216(0)

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wyh si rhet lyerfehxpria dan a ksbiabin gisn nginame atht etrhe is an NUM ?isleno

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csalib2 adshe ,pu i ihnkt reuy’o ni het rwogn uoietsnq taedrh +1

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