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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(630)
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I htink eht aesnor oyu edne ot ctenji gsoprtdoioann in ihst sace si bceaseu yuo ened FHS nda LH to cpeduor .empsr FSH tmeitasuls eth eilorst lesc,l hwchi lnei hte esimruosefin sutelub nad help teh tonpgroaeasmi poucrde oetsa.mcrtypes tseesoeTntro is a pduoctr fo yidgLe slcel wenh rhyeet' idetlutmsa yb HL, os ieinjtcgn tsnoseteetro uwldo pbassy taht stpe tub it unol'dwt arelly leph htiw moips.anessgeetr oe,wrveH tjgniicen HnRG oasl eostn'd sndote' lreayl ehlp sceeuba uoy need atht letslpiua nHGR at igtnh ot kmae HL nad SFH awehrse t-cngaolnig nGRH longsaa ayltlauc deesearc HL nad HFS ctpnuordoi.

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m-ice  gnAddi on ot eht sewarn bvaeo. I swa skcut nebwete teh prdgnooatino enijicsnto adn epno.icmlhe tB,u mipceoelnh tacs to nicreesa yvittcai of RnGH ichwh hent rexets tsi effestc no hte .ytiutripa heT nma in tshi nuoiteqs dha his piitaruyt oemdevr eabescu of an enomada. o,S eh edesn the SHF and HL dirct.ely +28
mousie  eera!g maR vloe of eht piryatitu dwulo caes a edtfcii ni Gnsrntpadoioo L(,H H)SF dan fetrohere hgtionn to leiuamst eht ttssee ot emka es...rmp clnegpair the T iwth a tahpc ouwdl ton telistmua the setste to eamk rmspe nad if sih ixsa swa tnitac alhuhgto( sit t)no tihs wdulo ruetrhf wond tgraelue the iurodcpnot fo esmp.r I tneeidlmia hpimloeCne sbaeuce if eh oesdtn have T to udenci ienvgate uefcienln no het haypmslhtaou eh iwll veah esdacreni GRnH and hfruert regsiannci ti htiw pohnCimele oluwd not orcrcte eht diecift ni saoGditpo.ronn +5
neonem  Oh .h..ud that amske mhcu meor ees.sn asTnhk! Ps.. I utgohht eomclpehni swa omre fo a iltfretyi gdru orf o,emnw cines it csbolk tvgneeia kcbdfaee of gsrneteo on hte uiloth/rpmsytu.htaaapiy Btu in enm eth smytse is edurn eaekbcdf ued to esete,rosntot not greetsn.o +6
utap2001  hlepmenoic si eostrgen ,nolgaaeu mcpoiietetv santagoi,nt not evceetiff ni m.na 2. eTh enhmciams of picenoehlm is bkecafde isreecan of nGgRtH-&; nsreacie HL,F,HS ton vetceifef in yttpriiau ovmrlae e.aipntt +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)


 +3  upvote downvote
submitted by โˆ—asharm10(37)
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os hsi rpitutay omaedan wsa eerdv,om os rlpoyl paostgoondhr weer doeemvr wiht ,ti os fi uyo evgi rnhg it t'wno do nyatihng as it tacn; cdueopr HS/FHL so you ievg hlh/fs idytrlec to edcin roeieaspgemsnts adn sotte s.ssnetihy

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faus305  aehY sith mkaes a otl of scnei. eTh anitorre tirptaiuy upceodsr AGiTPF-L (FSH, H,L CTHA, T,HS Plcn,aiort dan hoGtrw .nHom)eor itrPiuyta amensoda rea tmso ynoclomm aclmsnapoirto ni eht arenroti a.tyuirpti eH is ujts nwo cgnitnoi eth tfescef of not ivhagn LH nda FS,H itiientrf.yl oS ew ndee to peeclar hsto,e aak iveg adnrsootpog.in +



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