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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(629)
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I hktin eht asnroe uoy deen to jcinet ndantpogsoori ni tish aecs si sbcueae yuo eend HFS adn HL ot prdeuoc emsp.r SFH utsmeislta het retolis esc,ll hchiw ienl teh rinsifeoeums tuelubs and eplh teh moenoarasptgi odrcpue ptyaste.romces tesoTterseno is a ortpcud fo eiLdyg slelc hnew eyret'h seutdtmail yb ,LH so egctijinn stotetoeresn woldu psabsy thta pest btu it d'utnwol lleyra elph tihw seise.ontagsmpre v,eeoHwr tnieigjnc HGnR also ento'sd deos'tn yllrea leph cesuaeb yuo ende thta iseplluat HGnR at nghti to eakm HL adn FSH rhwseae i-cangtolng GRnH gnsaaol uylactla esecdare HL and HSF poun.tirodc

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m-ice  iAdgdn on to the seranw bovea. I aws tkcsu ewtbnee the padgoonoirnt njnesiiotc nad ecepmi.hnlo ,But oeehcpmnli acst to acrniese tciviyta of nRGH chhwi nteh etexrs ist cesteff no eth tytpiiuar. ehT nma in itsh ostnequi had sih yuirtptia eemovdr abucsee of na d.onaaem o,S eh esend teh SFH adn HL c.dlreyit +28
mousie  eegr!a alm evoR of het irtitupya wdolu saec a tifcdei in sopoanoinGrdt ,(HL SF)H dan feehtroer gthnnoi to etmliasu hte tteses ot amek msr...ep arpgcnlie het T wthi a actph wuldo nto itlustema hte teetss to make mepsr dan if his sxia saw ttnica h(thoaglu sti otn) iths wlodu teurfhr ndow etueglar hte uontociprd fo .rmeps I adlieinmet polCinhmee cesubae if eh eonstd ahve T to idneuc ivateeng ncufeinel on teh ohtmslhaupay eh ilwl veha aecdrsnie HRGn dan ruethfr cisergnnia it ihwt Cmepeohnli dulow tno tecorrc het tifeicd in tas.odnrnGipoo +5
neonem  Oh ..u.hd ttah aekms cmuh mero ssee.n Tashk!n .Ps. I uhttgoh lenpehoimc saw omer fo a teiriyftl grdu orf o,wemn isnec it lcokbs naievtge fcbkeead of toesengr on hte yyatmluitutaph.irs/apoh uBt in mne het mtyses si edunr cfeabdek deu ot t,snotteeroes otn esrnt.oeg +6
utap2001  meepliconh si ntsgeero an,leuoag eiottecvpim agstaoitnn, otn vfeicetfe ni .amn 2. hTe nsemihmca fo pnhieeomcl is kbaceedf eaeirsnc fo g-tR&;HnG ercaesin ,LF,HHS nto feceteivf ni uiiyattpr elroamv tnite.pa +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)


 +3  upvote downvote
submitted by โˆ—asharm10(37)
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os ish apiuyrtt omeanad aws reeod,mv os lyoplr hotoordnspga reew rmveoed with ,it so fi you egiv hnrg ti w'ton do ihgnyant as it cat;n curedop FHSLH/ os ouy vieg /shhlf eyrctdli to icend spastgmnsireoee nda stteo hsssn.yiet

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faus305  heYa htis esamk a lto fo esi.cn The ernroiat yitrtuaip ursdcpoe iGLP-TAF S(H,F HL, AHC,T T,SH incor,aPlt dan oGwhtr o).Henomr taiutyrPi anedmsao era smot mconmlyo aonrptomiscla in hte eraroitn ttpiu.iray eH is jsut wno gniiotnc eht stcfefe of not anivgh LH adn SH,F yneitrili.tf So ew ndee to alercpe ,seoth aka iveg roodgspno.iant +



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