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Retired NBME 24 Answers

nbme24/Block 3/Question#4 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Injections of gonadotropins ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +18  upvote downvote
submitted by โˆ—neonem(630)
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I kntih the aoners you edne to tiejcn gioasnrnodpot ni ihts csae si csbueea ouy ndee SHF dan HL ot udercpo er.mps FSH sltieutsma eht lrteois sellc, hcwih leni het enfrmiisoesu bseutlu dna plhe teh eaooantsigpmr epcuord mresesttcop.ay etenotTrseso is a rocdtup of dyLieg lclse nweh 'reethy stitlueamd by ,HL os etnciinjg tstersenoteo woldu byssap atth sept btu ti wn'utldo larely phle iwth eognsisperte.ams ,vowHree jiencnitg nRGH osal 'nsetdo 'tsneod elaylr lehp eacbseu uyo dnee ttha uiatpesll GRHn ta hitgn ot akme LH dna SFH heaewrs ntogn-ilagc GRHn gsaloan lyltuaac caerdese LH adn HSF dctpo.iornu

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m-ice  gAdidn on ot eht nwaesr oevb.a I saw cukst etewben teh dgtnniorooap ecinsoijtn adn oem.inecplh uBt, iephclenmo tcsa ot cserenia aiictvyt of RnHG ihhcw hetn xterse tis festfce no het pa.tiituyr hTe mna in stih iqoutsne dha ihs rtupityia eoremvd ucesbea fo na .maaenod S,o he sdnee the FHS nad LH ct.ryield +28
mousie  re!gea voelR a m fo hte atiuytrip ludwo sace a etdciif ni ontaGrodionps (,HL FH)S and orehftree nhtgoni to sutmaile hte tseets ot amek ..s.emrp calrnepig het T hwti a pctha oludw nto auimltste het tstese ot amek emsrp dna fi his xias was ttinac uhgtoal(h sit not) ihts odlwu hruterf down ealgrtue eht odiorntucp of .smrep I aiteemindl nmehieploC buasece if eh onedst eahv T ot udneic itveegna neiuefcln on teh mpsyhltouaha he lilw eahv riensdace nHGR and feuhtrr crisnneaig it tihw nehiColmep lwdou ont crrceto eht etficdi in Gsotpdnaro.nio +5
neonem  Oh u...hd thta eskam mhuc mroe sen.se anhksT! .P.s I touhthg nclehmipeo saw eorm of a tlfiiyter dgru orf owem,n esnci it boklcs ianteevg bkcfaeed fo goetnser on hte miyua/tya.otrithalpsuhp tBu ni mne het tesysm is uernd kaecbfed deu ot settetonsr,oe otn engtors.e +6
utap2001  lime hopenc si tgeosrne guaeno,al itipcomevte ittosgann,a not ecevtfief ni n.am .2 hTe ammceishn of coielmpenh is defeckab cneresai fo t&-GRHg;n csiranee HF,L,SH ont cefieftev ni tuaptryii vamlreo t.ipntae +1

Obviously the FSH -> spermatogenesis answer is the main idea, but I also think giving exogenous testosterone might actually impair levels of Testosterone in the testes as the concentration needs to be much higher in the testes for functionality due to a binding protein that is produced under stimulation by LH (which would be under neg feedback from exogenous testosterone)

+2/- cmun777(37)

I agree with below, sertoli cells release a testosterone binding protein in response to FSH in order to radically increase testosterone levels within the seminiferous tubules. That is why individuals who take exogenous testosterone have decreased fertility even while taking T.

+2/- lowyield(43)


 +3  upvote downvote
submitted by โˆ—asharm10(37)
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so hsi upatytir oamdane swa oevrm,ed so rpyllo atrghdnsopoo eerw edvorme itwh it, so fi yuo iegv rgnh ti ow'nt do gyiahnnt sa it ;actn odcpuer SH/FLH so you vieg h/lfsh rytliedc ot cnide egsnprtemaiseos and oetst .itenssysh

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faus305  Yahe ihts semka a otl of isce.n hTe ienaortr ritapiuyt reupsocd L-ATPGFi ,(FHS HL, HT,AC HT,S ,tnarliPco nad hwoGrt He.oonm)r rPiauiytt aandsmeo ear toms cynmlmoo msoonraaclipt in het roeinatr yitrit.apu He si sujt onw cinogtni hte fesfcte of not ahignv HL and SHF, tifirt.ileny So we dene to raecpel oet,hs aak gvei srono.ongitapd +



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