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NBME 24 Answers

nbme24/Block 1/Question#35 (32.3 difficulty score)
A 1616-g (3-lb 9-oz) male newborn is ...
Bronchopulmonary dysplasia🔍
tags: newborn 

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Baby developed RDS --> guven O2 as Rx --> complications of O2 herapy in neonated = RIB (FA 2019) R = Retinopathy of prematurity I = Inraventricular hemorrhage B = Bronchopulmonary dysplasia

peridot  RDS (respiratory distress syndrome) and O2 therapy complications are described on p.647 in FA 2019! +  
peridot  This is due to free radicles, which is also briefly touched upon on p. 210 of FA 2019 +  
peridot  radicals* +  

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submitted by seagull(1112),
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shiT ainftn sah ogeyxn tcyxtoii ued to fere dicrala nnoaie.tger Fere idlcasra dgaaem teh ulgn cmprahneay eildnga to oissirbf dan lipsysaad lrm(aaobn ).rtgwho

link981  Per American Lung Association: Bronchopulmonary dysplasia (BPD) is a form of chronic lung disease that affects newborns (mostly premature) and infants. It results from damage to the lungs caused by mechanical ventilation (respirator) and long-term use of oxygen. Most infants recover from BPD, but some may have long-term breathing difficulty. + Prematurely born infants have very few tiny air sacs (alveoli) at birth. The alveoli that are present tend to not be mature enough to function normal, and the infant requires respiratory support to breathe. Although life-saving, these treatments can also cause lung damage. +2  
jimdooder  Just to follow up on the concept, you would prevent this from occurring by decreasing the Fi02 to mid-low 90s. I believe this is tested on another form. +  

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submitted by link981(134),
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reP inraeAmc Lgun iAns:tiaosco rhcponaouyBlomrn islpaayds BP(D) si a frmo of hncoric ulng sdseiae tath fstfcae bwoennrs soym(lt ee)muarrtp dna fan.nsti It estlsur mrfo maeagd to het lnsgu dasceu by ihenccaalm tiennaltovi psroareri()t nad nemlogr-t esu fo gyexn.o Msto innfsat rcreoev from DBP, utb omse mya avhe gltrn-eom rhtgnabei .ifuyictdlf + rleutPyarme onbr iftsnan hvea eryv efw tyni ria cass elilv)a(o ta rbhit. The alleovi thta rae senptre ndte ot not eb uatmre uhgoen ot nnoitucf nlmroa, dna the fnnait euirerqs ryiterspoar upsrtop to te.ahrbe Aoghuhlt ,ilga-siefvn sheet ettmrtaesn nac soal aecus ugln aemdag

waterloo  per American Lunch Assoc... maaaaan what do I need to be to get this question right, a pulmonologist? +4  

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submitted by rongloz(1),

I think this is much simpler and is testing the understanding of basic path concepts of metaplasia and dysplasia. The question stem says there is bronchiolar metaplasia, and dysplasia is a reversible state of cells caused by longstanding hyperplasia or metaplasia (here in this case the baby presents 1 month later after the initial biopsy)