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NBME 24 Answers

nbme24/Block 1/Question#5 (36.9 difficulty score)
The 35-year-old woman indicated by the arrow ...
X-linked recessive🔍
tags: genetics process_of_elimination 

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X kelidn eesrisvec rehet cna rnvee be ayn aleM to Meal nfterras cneis hte ealm fsfnipgro esgt Y ofmr hta.fre eth dgeipere swohs elaM to lMea mssnrnisiato so isht tncaon be X ndkeli eserveisc




 +13  upvote downvote
submitted by monoclonal(19),
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hTe tinop eher i,s yhte ear kgnsai us to enmliitea eth lyon esrnaw htat si ton ibpeolss. I gto it .gownr erda llwe lsaefl

ergogenic22  nbme logic: "what if they all marry carrier wives" And doesn't everyone with autosomal dominant get it in the 2nd generation (unless incomplete penetrance) i feel dumb +8  
cavernosum  totally agree. what a st*pid qs! +  



 +2  upvote downvote
submitted by trazabone(12),
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yM rudsiaentdnng is htta if ntaersp rea teldeuran by lbdoo to oeths f,fadceet we susame ahtt yeht rae tno irarrsce ni( het escesrive .cae)s T,rhfreeoe if we aveh a eaml fehart aftfdcee twhi -xlkdein veesrceis ramerdi to a c-roin,enrra r'thsee on ywa yan of ish gpfirosfn wdlou eb .efefacdt

I"f neo aenprt is ont a ,iarcrer neth a hdlic nca olny intierh a sseidae alelel ofrm hte tehro napert. nI teehs lsobmp,er we can asesum taht nya iidvuanlid ygrmrina otni teh liymaf is nto a re"r ia.crdwi/snP~rcwce/nnihtsmCtt-sse.csi:ig/insopid.fptnte/rcs.u/wstc.otuutu/un

linwanrun1357  If we assume that they are not carriers (in the recessive case) Then how came it can be AR?!! +1  
catscan1979  ^exactly what's said above here. I think x-linked recessive is the least likely, but not impossible. +1  



The pedigree presents us with Male-to-Male transmission. There are two modes of inheritance where Male-to-Male transmission is impossible: 1) X-linked recessive 2) Mitochondrial inheritance




 +0  upvote downvote
submitted by ayhamai(0),

x-linked is not possible if the woman was not a carrier autosomal recessive is not possible if the woman was not a carrier so, why we choose x-linked




I thought there weren't supposed to be trick questions on these things.