welcome redditors!to snoo-finity ... and beyond!

NBME 23 Answers

nbme23/Block 2/Question#45

A 61-year-old man is prescribed fluoxetine for ...

Raphe nuclei

Login to comment/vote.

 +1  upvote downvote
submitted by dr.xx(44),

SSRIs produce a sustained increase in extracellular 5-HT in the dorsal raphe (DR), and this leads to autoinhibition of serotonergic neurons.

http://jgp.rupress.org/content/145/4/257

davidw  Pg 483 in firstaid has a good table of where the neurotransmitters work +1  




 +1  upvote downvote
submitted by sugaplum(57),

This is ridiculous but I could never keep these straight so meet my family:
Achey grandpa Meynert
Dope cousin VT with a side Ho* (who's names are just initials) SNc
Uncle and aunt Raphe and sara Cousin Gabby always screaming Na-Na-Na
norepi reminds me of the color blue, so locus ceruleus

paulkarr  LOL. Achey Granpa Meynert. I'm gonna steal this from you. +  




Serotonin is synthesised at the Raphe nucles. Hence, Fluoxetine which is and SSRI will prevent Serotonin synthesis since it maintains a high level of serotonin in the synapse.